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1.Citrus peel extract as inhibitor of ACYL coa-cholesterol-o-acyltransferase, inhibitor of macrophage-lipid complex accumulation on the arterial wall and preventive or treating agent for hepatic diseases 审中-公开
Title translation: 柑橘皮提取物作为ACYL coa-胆固醇-O-酰基转移酶的抑制剂,动脉壁上的巨噬细胞 - 脂质复合物积聚抑制剂和肝病预防或治疗剂公开(公告)号:US20010014357A1
公开(公告)日:2001-08-16
申请号:US09728917
申请日:2001-02-12
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: Song-Hae Bok , Tae-Sook Jeong , Ki-Hwan Bae , Yong-Bok Park , Myung-Sook Choi , Surk-Sik Moon , Yong-Kook Kwon , Eun-Sook Lee , Byung-Hwa Hyun , Yang-Kyu Choi , Chul-Ho Lee , Jun-Sung Lee , Kwang-Hee Son , Byoung-Mog Kwon , Young-Kook Kim , Doil Choi , Sung-Uk Kim , Ingyu Hwang , Jung-Ah Ahn , Young-Bae Park , Hyo-Soo Kim , Seong-Choon Choe
IPC: A61K035/78
CPC classification number: A23L2/56 , A23L33/10 , A23L33/105 , A23V2002/00 , A61K31/352 , A61K31/7048 , A61K36/752 , A61K2300/00 , A23V2250/2116
Abstract: Methods for inhibiting the activity of acyl CoA-cholesterol-o-acyltransferase, inhibiting the accumulation of macrophage-lipid complex on the arterial endothelium, and preventing or treating hepatic diseases in a mammal comprise administering a citrus peel extract thereto.
Abstract translation: 用于抑制酰基CoA-胆固醇-O-酰基转移酶的活性,抑制巨噬细胞 - 脂质复合物在动脉内皮上的积累以及预防或治疗哺乳动物的肝脏疾病的方法包括向其施用柑橘皮提取物。