公开(公告)号：US20230304989A1

公开(公告)日：2023-09-28

申请号：US18191388

申请日：2023-03-28

Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

Inventor： Seung-Wook CHI ,  Mi-Kyung Lee ,  Donghwa Lee ,  Sohee Oh

IPC: G01N33/487 ,  C12N15/113

CPC classification number: G01N33/48721 ,  C12N15/113 ,  C12N2310/531

Abstract: The disclosure relates to nanopore-based technology for screening of drugs against target RNA. According to the screening method of the disclosure, drugs targeting RNA can be efficiently screened even with a very small amount sample of picomolar concentration. The discovered drugs targeting RNA can be used in the treatment of diseases associated with RNAs.