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1.
公开(公告)号:US20230000923A1
公开(公告)日:2023-01-05
申请号:US17762313
申请日:2020-09-21
发明人: Janghwan KIM , Minhyung LEE , Mi Young SON , Young Joo JEON , Areum BAEK , Young Jeon LEE , Jincheol SEO , Cho Rok JUNG
IPC分类号: A61K35/30 , C12N5/0793 , A61P25/16
摘要: The present invention relates to a method for producing induced dopaminergic neuronal progenitors from adult cells using direct reprogramming, induced dopaminergic neuronal progenitors produced via the method and a use for same, wherein, as a result of having been directly reprogrammed from adult cells, the induced dopaminergic neuronal progenitors produced by means of the present invention can be transplanted inside a living body without the risk of oncogenicity, and have excellent proliferative capacity and dopaminergic neuronal differentiation potency, thus can be usefully utilized as a cell therapy product for Parkinson's disease.
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公开(公告)号:US20180322336A1
公开(公告)日:2018-11-08
申请号:US15779913
申请日:2016-11-30
申请人: KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY , KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
发明人: Sang Kuy HAN , Keyoung Jin CHUN , Kyu Tae CHANG , Young Jeon LEE , Yeung Bae JIN , Kang jin JEONG , Phil Yong KANG , Jung Joo HONG , Sang Rae LEE
IPC分类号: G06K9/00 , G06T7/73 , G06T7/593 , H04N13/204
摘要: The present invention includes: a three-dimensional moving image generation module for generating a moving image of an experiment target person; an object extraction module for extracting the experiment target person, separately from a background, from the moving image; an object definition module for defining an object by measuring a length, a size and a weight center of the object and extracting a depth image of the object; a behaviour pattern definition module for defining a basic behaviour pattern of the object by cumulatively analyzing a movement speed and movement time of the weight center of the corresponding object, and changes in the extracted depth data when the object defined by the object definition module is extracted by the object extraction module; and a behaviour pattern analysis module for analyzing and identifying a lasting time and a frequency of the basic behaviour pattern with respect to the object.
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