公开(公告)号：US20220017528A1

公开(公告)日：2022-01-20

申请号：US17311293

申请日：2019-12-05

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Chae Jo LIM ,  Kwang-Seok OH ,  Jeong Hyun LEE ,  Kyu Yang YI ,  Nack Jeong KIM ,  Byung Ho LEE ,  Ho Won SEO ,  Soo Hee KIM ,  Junyoung CHOI ,  Mi Young LEE ,  Ju Hee LEE

IPC: C07D487/04

Abstract: The present invention provides a compound having a specific chemical structure and having PDE9A inhibitory activity, or a pharmaceutically acceptable salt thereof. The present invention provides a composition containing the compound or a pharmaceutically acceptable salt thereof. The present invention provides a pharmaceutical use, for treating or preventing PDE9A-related diseases, of the compound according to the present invention, a salt thereof, and a composition containing the compound or salt. The present invention also provides a method for treating or preventing PDE9A-related diseases, the method comprising administering an effective amount of the compound according to the present invention, a salt thereof, or a composition containing the compound or salt to a subject in need of treatment.

公开(公告)号：US20220024932A1

公开(公告)日：2022-01-27

申请号：US17311287

申请日：2019-12-05

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Chae Jo LIM ,  Kwang-Seok OH ,  Jeong Hyun LEE ,  Kyu Yang YI ,  Nack Jeong KIM ,  Byung Ho LEE ,  Ho Won SEO ,  Soo Hee KIM ,  Junyoung CHOI ,  Mi Young LEE ,  Ju Hee LEE

IPC: C07D487/04

Abstract: The present invention provides a compound having a specific chemical structure and having PDE9A inhibitory activity, or a pharmaceutically acceptable salt thereof. The present invention provides a composition containing the compound or a pharmaceutically acceptable salt thereof. The present invention provides a pharmaceutical use, for treating or preventing PDE9A-related diseases, of the compound according to the present invention, a salt thereof, and a composition containing the compound or salt. The present invention also provides a method for treating or preventing PDE9A-related diseases, the method comprising administering an effective amount of the compound according to the present invention, a salt thereof, or a composition containing the compound or salt to a subject in need of treatment.