专利检索 ap:("KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION" OR "KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL") AND inv:"Joon-Young Kim" 第 1 页

1.

发明授权
Composition for preventing or treating renal fibrosis comprising dimethylfumarate as active ingredient 有权

公开(公告)号：US09724320B2

公开(公告)日：2017-08-08

申请号：US14767767

申请日：2013-02-20

申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION , KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL

发明人： In Kyu Lee , Keun Gyu Park , Chang Joo Oh , Han Jong Kim , Joon-Young Kim

IPC分类号： A61K31/225 , A61K9/00 , A61K9/14 , A61K9/20 , A23L33/10

CPC分类号： A61K31/225 , A23L33/10 , A23V2002/00 , A61K9/0053 , A61K9/0095 , A61K9/146 , A61K9/2059

摘要： The present invention relates to a composition for preventing or treating renal fibrosis comprising dimethylfumarate (DMF) as an active ingredient. The DMF according to the present invention has an excellent effect of reducing renal fibrosis by activating Nrf2 to inhibit TGF-β/Smad signaling, and thus is useful for preventing or treating renal fibrosis.