公开(公告)号：US20230174552A1

公开(公告)日：2023-06-08

申请号：US18097046

申请日：2023-01-13

申请人： KaNDy Therapeutics Limited

发明人： Mike TROWER ,  Monica LAZARO ,  Derek BUSH ,  David ELDER ,  Mary KERR

IPC分类号： C07D498/04 ,  A61P15/00 ,  A61K31/5383

CPC分类号： C07D498/04 ,  A61P15/00 ,  A61K31/5383 ,  C07B2200/13

摘要： The present invention generally relates to novel pharmaceutical formulations containing 2-[3,5-Bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-3-pyridinyl}-N,2-dimethylpropanamide, methods of preparation thereof and their use in medical therapy.

公开(公告)号：US20230382922A1

公开(公告)日：2023-11-30

申请号：US18228593

申请日：2023-07-31

申请人： KaNDy Therapeutics Limited

发明人： Mike TROWER ,  Monica LAZARO ,  Derek BUSH ,  David ELDER ,  Mary KERR

IPC分类号： C07D498/04 ,  A61P15/00 ,  A61K31/5383

CPC分类号： C07D498/04 ,  A61P15/00 ,  A61K31/5383 ,  C07B2200/13

摘要： The present invention generally relates to novel pharmaceutical formulations containing 2-[3,5-Bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl) hexahydropyrazino [2,1-c] [1,4]oxazin-8(1H)-yl]-3-pyridinyl}-N,2-dimethylpropanamide, methods of preparation thereof and their use in medical therapy.