公开(公告)号：US20130217021A1

公开(公告)日：2013-08-22

申请号：US13543831

申请日：2012-07-08

申请人： Kai-yun CHEN ,  Chung-che WU ,  Yung-hsiao CHIANG

发明人： Kai-yun CHEN ,  Chung-che WU ,  Yung-hsiao CHIANG

IPC分类号： C12Q1/68 ,  G01N33/573 ,  G01N21/76

CPC分类号： C12Q1/6881 ,  C12Q2600/158 ,  G01N33/6896

摘要： The present invention discloses a method for detecting and examining traumatic brain injury (TBI) in vitro. The method is according to the principle of expression of Etk/Bmx protein which is correspondingly increased when TBI occurs, so that the Etk/Bmx protein is defined as a quantification reference indicator specific for neurological injury degree of TBI. Thus, the method can be used to detect the expression of the Etk/Bmx protein for examining and evaluating the neurological injury degree of TBI occurred due to an external impact.

摘要翻译： 本发明公开了一种在体外检测和检查创伤性脑损伤（TBI）的方法。 该方法是根据Etk / Bmx蛋白的表达原理，TBI发生时相应增加，使得Etk / Bmx蛋白被定义为TBI神经损伤程度的定量参考指标。 因此，该方法可用于检测Etk / Bmx蛋白的表达，用于检查和评估由于外部影响而发生的TBI的神经损伤程度。

公开(公告)号：US20140363820A1

公开(公告)日：2014-12-11

申请号：US14304999

申请日：2014-06-16

申请人： Kai-yun CHEN ,  Chung-che Wu ,  Yung-hsiao Chiang

发明人： Kai-yun CHEN ,  Chung-che Wu ,  Yung-hsiao Chiang

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q2600/158 ,  G01N33/6896

摘要： The present invention discloses a method for detecting and examining traumatic brain injury (TBI) in vitro. The method is according to the principle of expression of Etk/Bmx mRNA which is correspondingly increased when TBI occurs, so that the Etk/Bmx mRNA is defined as a quantification reference indicator specific for neurological injury degree of TBI. Thus, the method can be used to detect the expression of the Etk/Bmx mRNA for examining and evaluating the neurological injury degree of TBI occurred due to an external impact.

摘要翻译： 本发明公开了一种在体外检测和检查创伤性脑损伤（TBI）的方法。 该方法根据Etk / Bmx mRNA的表达原理，TBI发生时相应增加，使Etk / Bmx mRNA定义为特异性TBI神经损伤程度的定量参考指标。 因此，该方法可用于检测Etk / Bmx mRNA的表达，用于检查和评估由于外部影响而发生的TBI的神经损伤程度。