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公开(公告)号：US20070287694A1
公开(公告)日：2007-12-13
申请号：US11756203
申请日：2007-05-31
IPC分类号： A61K31/55 , A61K31/553 , C07D487/04
CPC分类号： C07D487/04
摘要： The invention encompasses compounds as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译： 本发明包括化合物以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US07547690B2
公开(公告)日：2009-06-16
申请号：US12039239
申请日：2008-02-28
申请人： Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人： Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号： A61P31/00 , A61K31/55 , C07D223/14
CPC分类号： C07D519/00 , C07D487/04
摘要： The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译： 本发明包括式I化合物，包括药学上可接受的盐，以及使用这些化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US07452876B2
公开(公告)日：2008-11-18
申请号：US11756203
申请日：2007-05-31
IPC分类号： A61K31/55 , A61P31/00 , C07D223/14
CPC分类号： C07D487/04
摘要： The invention encompasses compounds as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译： 本发明包括化合物以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US07541353B2
公开(公告)日：2009-06-02
申请号：US12045874
申请日：2008-03-11
申请人： Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人： Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号： A61P31/00 , A61K31/55 , C07D223/14
CPC分类号： C07D487/04
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号：US20080227769A1
公开(公告)日：2008-09-18
申请号：US12039239
申请日：2008-02-28
申请人： Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人： Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号： A61K31/397 , C07D223/14 , A61P31/12 , A61K31/55
CPC分类号： C07D519/00 , C07D487/04
摘要： The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译： 本发明包括式I化合物，包括药学上可接受的盐，以及使用这些化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US20080226591A1
公开(公告)日：2008-09-18
申请号：US12045874
申请日：2008-03-11
申请人： Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
发明人： Robert G. Gentles , Xiaofan Zheng , Min Ding , Yong Tu , Ying Han , Piyasena Hewawasam , John F. Kadow , John A. Bender , Kap-Sun Yeung , Katharine A. Grant-Young , Thomas W. Hudyma
IPC分类号： A61K31/55 , C07D487/04 , A61K38/21 , C07D491/08 , A61K38/20 , C07D471/04
CPC分类号： C07D487/04
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号：US07473688B2
公开(公告)日：2009-01-06
申请号：US11516435
申请日：2006-09-06
申请人： Carl P. Bergstrom , John A. Bender , Robert G. Gentles , Piyasena Hewawasam , Thomas W. Hudyma , John F. Kadow , Scott W. Martin , Alicia Regueiro-Ren , Kap-Sun Yeung , Yong Tu , Katharine A. Grant-Young , Xiaofan Zheng
发明人： Carl P. Bergstrom , John A. Bender , Robert G. Gentles , Piyasena Hewawasam , Thomas W. Hudyma , John F. Kadow , Scott W. Martin , Alicia Regueiro-Ren , Kap-Sun Yeung , Yong Tu , Katharine A. Grant-Young , Xiaofan Zheng
IPC分类号： A61K31/55 , A61P31/00 , C07D223/14
CPC分类号： C07D491/14 , C07D487/04
摘要： The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
摘要翻译： 本发明包括式I，II，III和IV的化合物和盐以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US20080226590A1
公开(公告)日：2008-09-18
申请号：US12045766
申请日：2008-03-11
申请人： John A. Bender , Robert G. Gentles , Ying Han , Yong Tu , Zhong Yang , Kap-Sun Yeung , Katharine A. Grant-Young
发明人： John A. Bender , Robert G. Gentles , Ying Han , Yong Tu , Zhong Yang , Kap-Sun Yeung , Katharine A. Grant-Young
IPC分类号： A61K31/55 , C07D487/04 , A61P31/12 , A61K38/20 , A61K38/21 , C07D471/04
CPC分类号： C07D487/04
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号：US07521444B2
公开(公告)日：2009-04-21
申请号：US12045766
申请日：2008-03-11
申请人： John A. Bender , Robert G. Gentles , Ying Han , Yong Tu , Zhong Yang , Kap-Sun Yeung , Katharine A. Grant-Young
发明人： John A. Bender , Robert G. Gentles , Ying Han , Yong Tu , Zhong Yang , Kap-Sun Yeung , Katharine A. Grant-Young
IPC分类号： A61P31/00 , A61K31/55 , C07D223/14
CPC分类号： C07D487/04
摘要： The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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公开(公告)号：US08536338B2
公开(公告)日：2013-09-17
申请号：US13470727
申请日：2012-05-14
申请人： Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
发明人： Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
IPC分类号： A61K31/4355 , C07D491/044
CPC分类号： C07D471/04 , C07D209/42 , C07D333/68 , C07D491/048
摘要： The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
摘要翻译： 本公开提供式I，II，III，IV和V的化合物，包括它们的盐，以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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