Oncolytic viruses for the treatment of neoplasms having activated PP2A or Rac
    1.
    发明申请
    Oncolytic viruses for the treatment of neoplasms having activated PP2A or Rac 审中-公开
    用于治疗活化PP2A或Rac的肿瘤的溶瘤病毒

    公开(公告)号:US20050019308A1

    公开(公告)日:2005-01-27

    申请号:US10886022

    申请日:2004-07-06

    CPC分类号: A61K35/765 C12N2720/12232

    摘要: Methods for treating neoplasms, by administering oncolytic viruses to a neoplasm having activated PP2A-like or Rac activities, are disclosed. The virus is administered so that it ultimately directly contacts target cancer cells. Combinations of more than one type and/or strain of oncolytic viruses can be used. Of particular interest is the use of reovirus.

    摘要翻译: 公开了通过对具有活化的PP2A样或Rac活性的肿瘤施用溶瘤病毒来治疗肿瘤的方法。 施用病毒使其最终直接接触目标癌细胞。 可以使用多于一种类型和/或菌株的溶瘤病毒的组合。 特别感兴趣的是使用呼肠孤病毒。