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公开(公告)号:US08030277B2
公开(公告)日:2011-10-04
申请号:US11055967
申请日:2005-02-14
申请人: Kei Yamana , Yukimi Nagasawa , Hitoshi Wada , Yoshinori Kasahara
发明人: Kei Yamana , Yukimi Nagasawa , Hitoshi Wada , Yoshinori Kasahara
IPC分类号: A61K38/17
摘要: A polypeptide having the amino acid sequence as set forth in SEQ ID NO: 2, 4, or 6, a DNA encoding the same, and an antibody against said polypeptide, and the use thereof. The above amino acid sequence has a homology with chondromodulin-I that has an effect of controlling the growth and differentiation of chondrocytes and inhibiting angiogenesis.
摘要翻译: 具有SEQ ID NO:2,4或6所示氨基酸序列的多肽,编码该氨基酸序列的DNA和针对所述多肽的抗体及其用途。 上述氨基酸序列与软骨调节素-I具有同源性,其具有控制软骨细胞的生长和分化并抑制血管发生的作用。
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公开(公告)号:US20050171018A1
公开(公告)日:2005-08-04
申请号:US11055967
申请日:2005-02-14
申请人: Kei Yamana , Yukimi Nagasawa , Hitoshi Wada , Yoshinori Kasahara
发明人: Kei Yamana , Yukimi Nagasawa , Hitoshi Wada , Yoshinori Kasahara
IPC分类号: A61K38/00 , A61K38/17 , C07H21/04 , C07K14/51 , C07K14/705 , C07K16/22 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N15/12 , C12P21/08 , A61K38/19
摘要: A polypeptide having the amino acid sequence as set forth in SEQ ID NO: 2, 4, or 6, a DNA encoding the same, and an antibody against said polypeptide, and the use thereof. The above amino acid sequence has a homology with chondromodulin-I that has an effect of controlling the growth and differentiation of chondrocytes and inhibiting angiogenesis.
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公开(公告)号:US20050272127A1
公开(公告)日:2005-12-08
申请号:US11196618
申请日:2005-08-04
申请人: Kei Yamana , Yukimi Nagasawa , Hitoshi Wada , Yoshinori Kasahara
发明人: Kei Yamana , Yukimi Nagasawa , Hitoshi Wada , Yoshinori Kasahara
IPC分类号: A61K38/00 , A61K38/17 , C07H21/04 , C07K14/51 , C07K14/705 , C07K16/22 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N15/12 , C12P21/08
摘要: A polypeptide having the amino acid sequence as set forth in SEQ ID NO: 2, 4, or 6, a DNA encoding the same, and an antibody against said polypeptide, and the use thereof. The above amino acid sequence has a homology with chondromodulin-I that has an effect of controlling the growth and differentiation of chondrocytes and inhibiting angiogenesis.
摘要翻译: 具有SEQ ID NO:2,4或6所示氨基酸序列的多肽,编码该氨基酸序列的DNA和针对所述多肽的抗体及其用途。 上述氨基酸序列与软骨调节素-I具有同源性,其具有控制软骨细胞的生长和分化并抑制血管发生的作用。
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公开(公告)号:US07575922B2
公开(公告)日:2009-08-18
申请号:US11196618
申请日:2005-08-04
申请人: Kei Yamana , Yukimi Nagasawa , Hitoshi Wada , Yoshinori Kasahara
发明人: Kei Yamana , Yukimi Nagasawa , Hitoshi Wada , Yoshinori Kasahara
IPC分类号: C12N15/85
摘要: A polypeptide having the amino acid sequence as set forth in SEQ ID NO: 2, 4, or 6, a DNA encoding the same, and an antibody against said polypeptide, and the use thereof. The above amino acid sequence has a homology with chondromodulin-I that has an effect of controlling the growth and differentiation of chondrocytes and inhibiting angiogenesis.
摘要翻译: 具有SEQ ID NO:2,4或6所示氨基酸序列的多肽,编码该氨基酸序列的DNA和针对所述多肽的抗体及其用途。 上述氨基酸序列与软骨调节素-I具有同源性,其具有控制软骨细胞的生长和分化并抑制血管发生的作用。
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