公开(公告)号：US09814707B2

公开(公告)日：2017-11-14

申请号：US15113932

申请日：2015-01-23

Applicant: Keio University

Inventor： Hideyuki Saya ,  Osamu Nagano ,  Shogo Okazaki

IPC: A61K31/454 ,  A61K31/655 ,  A61K45/06

CPC classification number: A61K31/454 ,  A61K31/655 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention is directed to provide cancer stem cell proliferation inhibitors and inducers of intracellular accumulation of reactive oxygen species. To this end, provided are cancer stem cell proliferation inhibitors and inducers of intracellular accumulation of reactive oxygen species in a cancer stem cell each containing pimozide or sertindole as an active ingredient.