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公开(公告)号:US20090208552A1
公开(公告)日:2009-08-20
申请号:US12364763
申请日:2009-02-03
申请人: Keith M. FAUCHER , Hui TANG , Paul MARTAKOS , Steve A. HERWECK , Theodore KARWOSKI , Allison SULLIVAN , Greg MELVILLE , Scott E. CORBEIL
发明人: Keith M. FAUCHER , Hui TANG , Paul MARTAKOS , Steve A. HERWECK , Theodore KARWOSKI , Allison SULLIVAN , Greg MELVILLE , Scott E. CORBEIL
IPC分类号: A61K9/00 , A61K47/44 , C07C53/00 , C07D307/02 , A61K38/13 , A61K31/4353 , B05D3/00 , A61P37/00
CPC分类号: A61L31/08 , A61F2/82 , A61F2250/0067 , A61K31/4353 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/606 , A61L2420/06 , A61L2430/00
摘要: Fatty acid-based, pre-cure-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided.
摘要翻译: 描述了基于脂肪酸的预固化衍生的生物材料,制备生物材料的方法以及将其用作药物递送载体的方法。 脂肪酸衍生的生物材料可以单独使用或与医疗装置组合使用以释放和局部递送一种或多种治疗剂。 还提供了形成和调整所述生物材料的性质的方法以及使用所述生物材料治疗哺乳动物的损伤的方法。