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公开(公告)号:US09127060B2
公开(公告)日:2015-09-08
申请号:US13994349
申请日:2011-12-09
申请人: Kenneth G. Geles , Bin-Bing Stephen Zhou , Lioudmila Gennadievna Tchistiakova , Yijie Gao , Joel Bard
发明人: Kenneth G. Geles , Bin-Bing Stephen Zhou , Lioudmila Gennadievna Tchistiakova , Yijie Gao , Joel Bard
CPC分类号: C07K16/28 , A61K2039/505 , C07K2317/34 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: The present invention provides for antibodies that bind to Notch1. The present disclosure also provides methods of making the antibodies, pharmaceutical compositions comprising these antibodies and methods of treating disorders with the antibodies and pharmaceutical compositions.
摘要翻译: 本发明提供了结合Notch1的抗体。 本公开还提供了制备抗体的方法,包含这些抗体的药物组合物和用抗体和药物组合物治疗病症的方法。
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公开(公告)号:US20130266594A1
公开(公告)日:2013-10-10
申请号:US13994349
申请日:2011-12-09
申请人: Kenneth G. Geles , Bin-Bing Stephen Zhou , Lioudmila Gennadievna Tchistiakova , Yijie Gao , Joel Bard
发明人: Kenneth G. Geles , Bin-Bing Stephen Zhou , Lioudmila Gennadievna Tchistiakova , Yijie Gao , Joel Bard
IPC分类号: C07K16/28
CPC分类号: C07K16/28 , A61K2039/505 , C07K2317/34 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: The present invention provides for antibodies that bind to Notch1. The present disclosure also provides methods of making the antibodies, pharmaceutical compositions comprising these antibodies and methods of treating disorders with the antibodies and pharmaceutical compositions.
摘要翻译: 本发明提供了结合Notch1的抗体。 本公开还提供了制备抗体的方法,包含这些抗体的药物组合物和用抗体和药物组合物治疗病症的方法。
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公开(公告)号:US09340774B2
公开(公告)日:2016-05-17
申请号:US13260459
申请日:2010-03-26
IPC分类号: C12N5/095 , G01N33/574
CPC分类号: C12N5/0695 , C12N2501/385 , C12N2501/60 , G01N33/5011
摘要: Isolated and enriched tumor-initiating cell populations, methods for preparing the same, and uses thereof.
摘要翻译: 分离和富集的肿瘤起始细胞群体,其制备方法及其用途。
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