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公开(公告)号:US20140127209A1
公开(公告)日:2014-05-08
申请号:US13791312
申请日:2013-03-08
申请人: Kenneth GRABSTEIN , William BRADY , Gordon KING , Natalie Winblade NAIRN , Kurt David SHANEBECK , Paul Heffner SLAGLE , Kenneth Christopher THORNTON , Michael Peter VANBRUNT , Andrea WANG , Hengyu XU
发明人: Kenneth GRABSTEIN , William BRADY , Gordon KING , Natalie Winblade NAIRN , Kurt David SHANEBECK , Paul Heffner SLAGLE , Kenneth Christopher THORNTON , Michael Peter VANBRUNT , Andrea WANG , Hengyu XU
IPC分类号: C07K16/46
CPC分类号: C07K16/244 , A61K2039/505 , A61K2039/507 , C07K16/248 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/40 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/76 , C07K2317/92
摘要: The invention relates inter alia to a bivalent, bispecific construct comprising an anti-IL-6 antibody, or derivative thereof, and an anti-IL-23 antibody, or derivative thereof and its use in therapy. The invention also relates to useful anti-IL-6 antibodies and anti-IL-23 antibodies.
摘要翻译: 本发明特别涉及包含抗IL-6抗体或其衍生物和抗IL-23抗体或其衍生物的二价双特异性构建体及其在治疗中的用途。 本发明还涉及有用的抗IL-6抗体和抗IL-23抗体。