公开(公告)号：US06369054B1

公开(公告)日：2002-04-09

申请号：US09601572

申请日：2000-08-03

申请人： Kirkor Sirinyan ,  Karin Horn ,  Ronald Helmut Stöcker ,  Rainer Sonneck

发明人： Kirkor Sirinyan ,  Karin Horn ,  Ronald Helmut Stöcker ,  Rainer Sonneck

IPC分类号： A61K3141

CPC分类号： A01N51/00 ,  A01N61/00 ,  A01N43/08 ,  A01N31/02 ,  A01N25/02 ,  A01N2300/00

摘要： The present invention relates to water-containing formulations for the dermal control of parasitic insects and mites on humans, said formulations having the following composition: a—agonists or antagonists of the nicotinic acetylcholine receptors of insects in a concentration of from 0.0001 to 7.5% by weight, based on the overall weight of the formulation; b—water in a concentration of from 20 to 50% by weight, based on the overall weight of the formulation; c—acyclic alcohols in a concentration of from 20 to 50% by weight, based on the overall weight of the formulation; d—solvents from the group consisting of cyclic carbonates and lactones in a concentration of from 2.5 up to 20.0% by weight, based on the overall weight of the formulation; e—optionally further auxiliaries from the group consisting of thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, tackifiers, emulsifiers, in a concentration of from 0 up to 30% by weight, based on the overall weight of the formulation.

摘要翻译： 本发明涉及用于真皮控制人类寄生昆虫和螨虫的含水制剂，所述制剂具有以下组成：昆虫的烟碱乙酰胆碱受体的α-激动剂或拮抗剂，其浓度为0.0001至7.5％，浓度为 重量，基于制剂的总重量;基于制剂的总重量，浓度为20至50重量％的b-水;浓度为20至50重量％的c-无环醇 ，基于制剂的总重量;基于制剂总重量的2.5重量％至20.0重量％的来自环状碳酸酯和内酯的d-溶剂; e-任选的另外的辅助剂 基于总重量的浓度为0至30重量％的增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，增粘剂，乳化剂组成的组 公式。

公开(公告)号：US06300348B1

公开(公告)日：2001-10-09

申请号：US09142892

申请日：1998-09-16

申请人： Kirkor Sirinyan ,  Ulrich Heukamp ,  Hubert Dorn ,  Ronald Helmut Stöcker ,  Rainer Sonneck ,  Rosemary Peter

发明人： Kirkor Sirinyan ,  Ulrich Heukamp ,  Hubert Dorn ,  Ronald Helmut Stöcker ,  Rainer Sonneck ,  Rosemary Peter

IPC分类号： H01N5100

CPC分类号： A01N51/00 ,  Y10S514/83 ,  A01N43/28 ,  A01N25/02 ,  A01N2300/00

摘要： The present invention relates to formulations for the dermal control of parasitic insects on humans, having the following composition agonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 0.0001 to 12.5% by weight based on the overall weight of the formulation; solvents from the group of the cyclic carbonates in a concentration of from 2.5 to 99.9999% by weight based on the overall weight of the formulation; if desired, further solvents from the group consisting of the alcohols in a concentration of from 0 to 95% by weight based on the overall weight of the formulation; if desired, further auxiliaries from the group of the thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0 up to 30% by weight based on the overall weight of the formulation.

摘要翻译： 本发明涉及用于对人类寄生虫进行真皮控制的制剂，其具有以下配合物，其浓度为制剂总重量的0.0001至12.5重量％的昆虫的烟碱能乙酰胆碱受体的组成或拮抗剂;溶剂 来自环状碳酸酯的基团，其浓度为制剂总重量的2.5至99.9999重量％;如果需要，还可使用浓度为0至95重量％的醇的其它溶剂 基于制剂的总重量;如果需要，来自增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的组的其它助剂的浓度为0至30重量％，基于 制剂的总重量。