公开(公告)号：US20060004101A1

公开(公告)日：2006-01-05

申请号：US11165217

申请日：2005-06-24

申请人： Kiwamu Okita ,  Isao Sakaida ,  Yoshihiro Morinaga ,  Shoji Fujitani

发明人： Kiwamu Okita ,  Isao Sakaida ,  Yoshihiro Morinaga ,  Shoji Fujitani

IPC分类号： A61K31/198

CPC分类号： A23L1/3051 ,  A23K20/142 ,  A23L33/175 ,  A23V2002/00 ,  A61K31/198 ,  A61K2300/00 ,  A23V2250/0626 ,  A23V2250/0628 ,  A23V2250/0654

摘要： The present invention provides a prophylactic or therapeutic agent, a pharmaceutical composition and a health-promoting food, which are used for human or other animal for the inhibition of the onset or progress of liver cancer, namely, an inhibitor of the onset or progress of liver cancer, which contains isoleucine, leucine and valine as active ingredients, wherein the weight ratio of isoleucine, leucine and valine is preferably 1:1.5 to 2.5:0.8 to 1.7 and the daily dose is 2.0 g to 50.0 g.

摘要翻译： 本发明提供了用于人或其他动物用于抑制肝癌的发病或进展的预防或治疗剂，药物组合物和促进健康的食物，即抑制剂的发病或进展的抑制剂 含有异亮氨酸，亮氨酸，缬氨酸作为活性成分的肝癌，其中异亮氨酸，亮氨酸，缬氨酸的重量比优选为1:1.5〜2.5:0.8〜1.7，日剂量为2.0g〜50.0g。

公开(公告)号：US09271521B2

公开(公告)日：2016-03-01

申请号：US11165217

申请日：2005-06-24

申请人： Kiwamu Okita ,  Isao Sakaida ,  Yoshihiro Morinaga ,  Shoji Fujitani

发明人： Kiwamu Okita ,  Isao Sakaida ,  Yoshihiro Morinaga ,  Shoji Fujitani

IPC分类号： A61K31/198 ,  A23L1/305 ,  A61P1/16 ,  A23K1/16

CPC分类号： A23L1/3051 ,  A23K20/142 ,  A23L33/175 ,  A23V2002/00 ,  A61K31/198 ,  A61K2300/00 ,  A23V2250/0626 ,  A23V2250/0628 ,  A23V2250/0654

摘要： The present invention provides a prophylactic or therapeutic agent, a pharmaceutical composition and a health-promoting food, which are used for human or other animal for the inhibition of the onset or progress of liver cancer, namely, an inhibitor of the onset or progress of liver cancer, which contains isoleucine, leucine and valine as active ingredients, wherein the weight ratio of isoleucine, leucine and valine is preferably 1:1.5 to 2.5:0.8 to 1.7 and the daily dose is 2.0 g to 50.0 g.

公开(公告)号：US20080064302A1

公开(公告)日：2008-03-13

申请号：US11898211

申请日：2007-09-10

申请人： Shoji Fujitani

发明人： Shoji Fujitani

IPC分类号： B24B7/30 ,  B24D11/00

CPC分类号： B24B37/26

摘要： A polishing pad is placed on a polishing apparatus including a polishing platen which is rotatable and on which the polishing pad is placed, a substrate retaining mechanism, and a supplying mechanism for supplying a polishing agent on an upper surface of the polishing pad, the polishing pad having grooves extending from the center of the polishing pad to the outer edge thereof, the groove becoming gradually deeper from the center of the polishing pad toward the outer edge portion thereof so that the depth of the groove is the largest at the outer edge portion, thereby allowing a slurry to be smoothly discharged from the upper surface of the polishing platen.

摘要翻译： 抛光垫被放置在抛光装置上，该抛光装置包括可旋转的研磨台板，抛光垫放置在其上，基板保持机构和用于在抛光垫的上表面上提供抛光剂的供给机构，抛光垫 衬垫具有从抛光垫的中心延伸到其外边缘的凹槽，凹槽从抛光垫的中心朝向其外边缘部分逐渐变深，使得凹槽的深度在外边缘部分处最大 从而允许浆料从研磨台板的上表面平滑地排出。

公开(公告)号：US20050197398A1

公开(公告)日：2005-09-08

申请号：US11066312

申请日：2005-02-28

申请人： Ichiro Sonaka ,  Shoji Fujitani

发明人： Ichiro Sonaka ,  Shoji Fujitani

IPC分类号： A61K31/198 ,  A61P1/16

CPC分类号： A61K31/198 ,  A61K2300/00

摘要： Pharmaceutical compositions which contain isoleucine, leucine, valine, and alanine as active ingredients, are useful for treating liver diseases such as hepatitis, liver cirrhosis, liver cancer, and the like via maintenance and improvement of albumin level in blood. In preferred embodiments, the mass ratio of isoleucine:leucine:valine is 1:1.9 to 2.2:1.1 to 1.3; the mass ratio of the total mass of isoleucine, leucine and valine: alanine is 1:0.05 to 10; and a daily dose per person contains isoleucine in an amount of 0.2-30.0 g, leucine in an amount of 0.2-30.0 g, valine in an amount of 0.2-30.0 g, and alanine in an amount of 0.2-50.0 g.

摘要翻译： 含有异亮氨酸，亮氨酸，缬氨酸和丙氨酸作为活性成分的药物组合物可用于通过维持和改善血液中的白蛋白水平来治疗肝脏疾病如肝炎，肝硬化，肝癌等。 在优选的实施方案中，异亮氨酸：亮氨酸：缬氨酸的质量比为1：1.9至2.2：1.1至1.3; 异亮氨酸，亮氨酸和缬氨酸：丙氨酸总质量的质量比为1:0.05至10; 并且每人每日剂量含有0.2-30.0g的异亮氨酸，0.2-30.0g的亮氨酸，0.2-30.0g的缬氨酸和0.2-50.0g的丙氨酸。