公开(公告)号：US20240295561A1

公开(公告)日：2024-09-05

申请号：US18569833

申请日：2022-03-08

Applicant: Konica Minolta, Inc.

Inventor： MANAMI MASUBUCHI ,  NOBUHISA HARADA ,  MASARU TAKAHASHI

IPC: G01N33/58 ,  G01N21/64

CPC classification number: G01N33/582 ,  G01N21/6428 ,  G01N2021/6441

Abstract: A quantification method in the present invention is a quantification method for quantifying three or more kinds of quantification-target substances contained in a plurality of samples collected from one specimen, and includes a quantification step of quantifying the three or more kinds of quantification-target substances in each of the plurality of samples on the basis of a detection value derived from a first labeling substance that labels a reference substance commonly contained in the plurality of samples. In the present invention, three or more kinds of observation-target substances can be observed or quantified without requiring many kinds of labeling substances even when staining conditions are different from each other. That is, the observation-target substances (a reference substance and quantification-target substances other than the reference substance) can be each observed or quantified using a smaller number of kinds of labeling substances than the number of kinds of the observation-target substances.

公开(公告)号：US20220229047A1

公开(公告)日：2022-07-21

申请号：US17612919

申请日：2020-06-15

Applicant: Konica Minolta, Inc.

Inventor： YUKI MIYAKE ,  DAISUKE TOMIOKA ,  MASARU TAKAHASHI

IPC: G01N33/533 ,  C12N15/115

Abstract: The present invention provides a linked body for fluorescent labeling agents, the linked body suppressing noise due to specific adsorption in performing quantification and localization analysis of a target substance. The present invention is a linked body for fluorescent labeling agents obtained by bonding a probe molecule to a bonding group via a linker, in which a labeling ratio of the bonding group to the probe molecule is 3 or more.