公开(公告)号：US10585022B2

公开(公告)日：2020-03-10

申请号：US15216938

申请日：2016-07-22

Applicant: Korea Institute of Science and Technology

Inventor： Rhokyun Kwak ,  Ji Yoon Kang ,  Jaesung Park ,  Siwoo Cho

IPC: C12Q1/68 ,  G01N1/40 ,  G01N27/447 ,  C12Q1/6806 ,  C12Q1/00

Abstract: Provided are an extracellular vesicle collecting apparatus using an electrode and a porous membrane and a method for using the same. The extracellular vesicle collecting apparatus includes i) an upper frame in which a pair of through holes is disposed so that a buffer solution flows therethrough, ii) a buffer tube which is inserted in the through holes and in which the buffer solution flows, iii) a positive electrode disposed on the upper frame, iv) a porous membrane located below the upper frame, v) a spacer which is located below the porous membrane and has a hollow space disposed therein, vi) a plurality of guide tubes through which a blood flows in the hollow space, vii) a lower frame which is coupled to the upper frame to be opposite to the upper frame and receives the porous membrane and the spacer therein, and viii) a negative electrode provided below the lower frame. Extracellular vesicles contained in the blood are collected by the porous membrane.