公开(公告)号：US20240287023A1

公开(公告)日：2024-08-29

申请号：US18634587

申请日：2024-04-12

申请人： Kura Oncology, Inc.

发明人： Xuefeng Zhu ,  Pingda Ren ,  Zhu Bai ,  Wanting Xiong ,  Dan Xu ,  Yahu Arthur Liu

IPC分类号： C07D401/10 ,  A61P35/00 ,  C07D491/044

CPC分类号： C07D401/10 ,  A61P35/00 ,  C07D491/044

摘要： The present invention relates to macrocyclic compounds of any one of Formula (I), or a pharmaceutically acceptable form thereof, pharmaceutical compositions comprising the same, methods of preparing the same, and methods of treating cancer dependent on a farnesylated protein, using the same.

公开(公告)号：US12018011B2

公开(公告)日：2024-06-25

申请号：US18329479

申请日：2023-06-05

申请人： Kura Oncology, Inc.

发明人： Xuefeng Zhu ,  Pingda Ren ,  Zhu Bai ,  Wanting Xiong ,  Dan Xu ,  Yahu Arthur Liu

IPC分类号： A61P35/00 ,  C07D401/10 ,  C07D491/044

CPC分类号： C07D401/10 ,  A61P35/00 ,  C07D491/044

摘要： The present invention relates to macrocyclic compounds of any one of Formula (I), or a pharmaceutically acceptable form thereof, pharmaceutical compositions comprising the same, methods of preparing the same, and methods of treating cancer dependent on a farnesylated protein, using the same.

公开(公告)号：US20230322711A1

公开(公告)日：2023-10-12

申请号：US18329479

申请日：2023-06-05

申请人： Kura Oncology, Inc.

发明人： Xuefeng Zhu ,  Pingda Ren ,  Zhu Bai ,  Wanting Xiong ,  Dan Xu ,  Yahu Arthur Liu

IPC分类号： C07D401/10 ,  C07D491/044 ,  A61P35/00

CPC分类号： C07D401/10 ,  A61P35/00 ,  C07D491/044

摘要： The present invention relates to macrocyclic compounds of any one of Formula (I), or a pharmaceutically acceptable form thereof, pharmaceutical compositions comprising the same, methods of preparing the same, and methods of treating cancer dependent on a farnesylated protein, using the same.