公开(公告)号：US09902711B2

公开(公告)日：2018-02-27

申请号：US15106398

申请日：2014-12-19

Applicant: LABORATORIOS DEL DR. ESTEVE S.A.

Inventor： Félix Cuevas-Cordobés ,  Carmen Almansa-Rosales ,  Monica Garcia Lopez ,  Eva Maria Ayet Galcera ,  Maria Teresa Serafini Cabanes

IPC: C07D401/06 ,  C07D401/14

CPC classification number: C07D401/06 ,  C07D401/14

Abstract: The present invention relates to compounds having dual pharmacological activity towards both the sigma (σ) receptor, and the μ-opiod receptor and more particularly to piperidene compounds having this pharmacological activity, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.