公开(公告)号：US20190367512A1

公开(公告)日：2019-12-05

申请号：US16477249

申请日：2018-01-10

Applicant: LEO Pharma A/S

Inventor： Jens LARSEN ,  Mogens LARSEN ,  Lars Kyhn RASMUSSEN ,  Andreas RITZEN ,  Tine Marianne DUUS

IPC: C07D471/04

Abstract: The present invention relates to a compound according to formula (I) or pharmaceutically acceptable salts, hydrates, or solvates thereof; wherein R1 is C1-alkyl, R2 is C1-alkyl, R3 is C2-alkyl, R4 is hydrogen, R5 is hydrogen. The invention relates further to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to said compounds for use in the treatment autoimmune diseases and to intermediates for the preparation of said compounds.