-
公开(公告)号:US20220016060A1
公开(公告)日:2022-01-20
申请号:US17311616
申请日:2019-12-05
发明人: LYNE GAGNON , PIERRE LAURIN , FRANK CESARI
摘要: Methods, formulations/compositions and uses for improving at least one of liver histology, heart histology, kidney histology, adipose tissue histology and a metabolic parameter in a patient suffering from Alström syndrome are described, comprising administration of a pharmaceutical oral formulation comprising 2-(3-pentylphenyl)acetate or a pharmaceutically salt thereof and a pharmaceutically acceptable excipient at a daily dose of about 500 mg to about 1500 mg. The treatment is preferably for a period of more than 48 weeks and is not interrupted for 15 days or more.