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公开(公告)号:US11001552B2
公开(公告)日:2021-05-11
申请号:US16620001
申请日:2018-07-16
Applicant: LONZA LTD
Inventor: Michael Bersier , Anna Kulesza , Paul Hanselmann , Christof Aellig , Sarah Filliger
IPC: C07C201/08 , C07C205/58
Abstract: The invention discloses a method for preparation of 5-fluoro-2-methyl-3-nitrobenzoic acid and its methyl ester by conversion of 5-fluoro-2-methylbenzoic acid with fuming nitric acid and oleum and subsequent conversion with methanol.