公开(公告)号：US20180251420A1

公开(公告)日：2018-09-06

申请号：US15747510

申请日：2016-09-14

Applicant: LONZA LTD

Inventor： Christoph Taeschler ,  Ulrich Mayerhoeffer ,  Christophe Girard ,  Michael Bittel ,  Rolf Kalbermatten ,  Claudio Arnold ,  Stefan Garms ,  Christian Schnider ,  Stefan Tille ,  Manuel Favre ,  Guy Raboud ,  Kilian Schnydrig ,  Martin Venetz ,  Thomas Eggel

IPC: C07C201/04 ,  C07C203/00 ,  B01J19/18

CPC classification number: C07C201/04 ,  B01J19/1881 ,  B01J2219/00033 ,  B01J2219/00162 ,  B01J2219/00166 ,  C07C203/00

Abstract: The invention discloses a method for the continuous preparation of n-butyl nitrite with a low content of n-butanol comprising the reaction of n-butanol, an acid and NaNO2 in a continuous way, in which the n-butanol, an acid and NaNO2 are mixed in a mixing device which provides for a pressure drop of at least 1 bar; the acid is selected from the group consisting of HCI, H2SO4, formic acid, methanesulfonic acid, and mixtures thereof; and the amount of HCI is at least 1.02 molar equivalent based on the molar amount of n-butanol.

公开(公告)号：US10125087B2

公开(公告)日：2018-11-13

申请号：US15747510

申请日：2016-09-14

Applicant: LONZA LTD

Inventor： Christoph Taeschler ,  Ulrich Mayerhoeffer ,  Christophe Girard ,  Michael Bittel ,  Rolf Kalbermatten ,  Claudio Arnold ,  Stefan Garms ,  Christian Schnider ,  Stefan Tille ,  Manuel Favre ,  Guy Raboud ,  Kilian Schnydrig ,  Martin Venetz ,  Thomas Eggel

IPC: C07C201/04 ,  C07C203/00 ,  B01J19/18

Abstract: The invention discloses a method for the continuous preparation of n-butyl nitrite with a low content of n-butanol comprising the reaction of n-butanol, an acid and NaNO2 in a continuous way, in which the n-butanol, an acid and NaNO2 are mixed in a mixing device which provides for a pressure drop of at least 1 bar; the acid is selected from the group consisting of HCI, H2SO4, formic acid, methanesulfonic acid, and mixtures thereof; and the amount of HCI is at least 1.02 molar equivalent based on the molar amount of n-butanol.