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公开(公告)号：US09180133B2
公开(公告)日：2015-11-10
申请号：US14200100
申请日：2014-03-07
申请人： LABORATOIRE HRA-PHARMA , THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES
发明人： Lynnette Nieman , Andre Ulmann , Diana Blithe , Erin Gainer
摘要： The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids.
摘要翻译： 本发明涉及一种治疗子宫肌瘤的方法，该方法包括向有需要的患者施用有效量的17α-乙酰氧基-11β-[4-N，N-二甲基氨基 - 苯基）-19-去甲基-4- ，9-二烯-3,20-二酮（ulipristal）或其任何代谢产物。 更具体地，该方法可用于减少或停止患子宫肌瘤患者的出血和/或减小子宫肌瘤的大小。
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2.发明申请公开(公告)号：US20150018325A1
公开(公告)日：2015-01-15
申请号：US14499991
申请日：2014-09-29
申请人： LABORATOIRE HRA-PHARMA , The United States of America, as represented by the Secretary, Dept. of Health and Human Services
发明人： Andre Ulmann , Henri Camille Mathe , Erin Gainer , Diana Blithe
IPC分类号： A61K31/57
CPC分类号： A61K31/57
摘要： The invention provides a method for providing post coital contraception in a female subject, comprising providing the subject with a therapeutically effective amount of ulipristal acetate, between about 3 to about 5 days after unprotected intercourse.
摘要翻译： 本发明提供了一种在女性受试者中提供阴道避孕的方法，其包括向受试者提供治疗有效量的醋酸乌利司他，在无保护的性交后约3至约5天。
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公开(公告)号：US20130023506A1
公开(公告)日：2013-01-24
申请号：US13622892
申请日：2012-09-19
申请人： Laboratoire HRA-PHARMA , The United States of America, as represented by the Secretary, Dept. of Health and Human Services
发明人： Lynnette Nieman , Andre Ulmann , Diana Blithe , Erin Gainer
摘要： The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids.
摘要翻译： 本发明涉及一种治疗子宫肌瘤的方法，该方法包括向有需要的患者施用有效量的17α-乙酰氧基-11β-[4-N，N-二甲基氨基 - 苯基）-19-去甲基-4- ，9-二烯-3,20-二酮（ulipristal）或其任何代谢产物。 更具体地，该方法可用于减少或停止患子宫肌瘤患者的出血和/或减小子宫肌瘤的大小。
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公开(公告)号：US09682088B2
公开(公告)日：2017-06-20
申请号：US14872320
申请日：2015-10-01
申请人： LABORATOIRE HRA-PHARMA , THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES
发明人： Lynnette Nieman , Andre Ulmann , Diana Blithe , Erin Gainer
摘要： The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids.
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5.发明申请公开(公告)号：US20150174141A1
公开(公告)日：2015-06-25
申请号：US14637567
申请日：2015-03-04
发明人： Delphine Levy , Andre Ulmann , Henri Camille Mathe , Erin Gainer
IPC分类号： A61K31/57
CPC分类号： A61K31/57
摘要： The invention provides a method for providing post coital contraception in a female subject, comprising providing the subject with a therapeutically effective amount of ulipristal acetate, wherein the female subject is overweight or obese.
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6.发明申请METHOD FOR POST COITAL CONTRACEPTION IN OVERWEIGHT OR OBESE FEMALE SUBJECTS USING ULIPRISTAL ACETATE 审中-公开过度使用醋酸乙烯酯的方法用于过度使用海绵体或使用雌激素公开(公告)号：US20150157643A1
公开(公告)日：2015-06-11
申请号：US14593449
申请日：2015-01-09
发明人： Delphine Levy , Andre Ulmann , Henri Camille Mathe , Erin Gainer
IPC分类号： A61K31/57
CPC分类号： A61K31/57
摘要： The invention provides a method for providing post coital contraception in a female subject, comprising providing the subject with a therapeutically effective amount of ulipristal acetate, wherein the female subject is overweight or obese.
摘要翻译： 本发明提供了一种在女性受试者中提供阴道避孕的方法，其包括向受试者提供治疗有效量的醋酸乌利司他，其中女性受试者超重或肥胖。
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公开(公告)号：US09283233B2
公开(公告)日：2016-03-15
申请号：US14635107
申请日：2015-03-02
申请人： LABORATOIRE HRA PHARMA , The United States of America, as represented by the Secretary,Department of Health and Human Services
CPC分类号： A61K31/573 , A61K9/0036 , A61K9/06 , A61K9/20 , A61K31/56 , A61K31/57
摘要： The invention relates to a method for on-demand contraception, which method comprises administering a progestogen agent or progesterone receptor modulator, such as 17a-acetoxy-11b-(4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal acetate) in a woman, within 72 hours before an intercourse or within 120 hours after the intercourse.
摘要翻译： 本发明涉及一种按需避孕方法，该方法包括施用孕激素或孕酮受体调节剂，例如17a-乙酰氧基-11β-（4-N，N-二甲基氨基 - 苯基）-19-去甲孕酮-4， 9-二烯-3,20-二酮（醋酸乌司他丁）在性交前72小时内或性交后120小时内。
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公开(公告)号：US10772897B2
公开(公告)日：2020-09-15
申请号：US16230802
申请日：2018-12-21
申请人： Laboratoire HRA-Pharma , The USA, As Represented by the Secretary, Department of Health and Human Services
摘要： The invention relates to a method for on-demand contraception, which method comprises administering a progestogen agent or progesterone receptor modulator, such as 17a-acetoxy-11b-[4-N, N-dimethylamino-phenyl)-19-norpregna-4, 9-diene-3, 20-dione (ulipristal acetate) in a woman, within 72 hours before an intercourse or within 120 hours after the intercourse.
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公开(公告)号：US20190209583A1
公开(公告)日：2019-07-11
申请号：US16230802
申请日：2018-12-21
申请人： Laboratoire HRA-Pharma , The USA, As Represented by the Secretary, Department of Health and Human Services
摘要： The invention relates to a method for on-demand contraception, which method comprises administering a progestogen agent or progesterone receptor modulator, such as 17a-acetoxy-11b-[4-N, N-dimethylamino-phenyl)-19-norpregna-4, 9-diene-3, 20-dione (ulipristal acetate) in a woman, within 72 hours before an intercourse or within 120 hours after the intercourse.
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公开(公告)号：US20150174140A1
公开(公告)日：2015-06-25
申请号：US14635107
申请日：2015-03-02
申请人： LABORATOIRE HRA PHARMA , The United States of America, as represented by the Secretary, Department of Health and Human Serv
CPC分类号： A61K31/573 , A61K9/0036 , A61K9/06 , A61K9/20 , A61K31/56 , A61K31/57
摘要： The invention relates to a method for on-demand contraception, which method comprises administering a progestogen agent or progesterone receptor modulator, such as 17a-acetoxy-11b-(4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal acetate) in a woman, within 72 hours before an intercourse or within 120 hours after the intercourse.
摘要翻译： 本发明涉及一种按需避孕方法，该方法包括施用孕激素或孕酮受体调节剂，例如17a-乙酰氧基-11β-（4-N，N-二甲基氨基 - 苯基）-19-去甲孕酮-4， 9-二烯-3,20-二酮（醋酸乌司他丁）在性交前72小时内或性交后120小时内。
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