公开(公告)号：US20220233671A1

公开(公告)日：2022-07-28

申请号：US17335573

申请日：2021-06-01

申请人： Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences

发明人： Yuefeng CHU ,  Shengli CHEN ,  Huafang HAO ,  Xinmin YAN ,  Lina MA ,  Yongsheng LIU

IPC分类号： A61K39/02 ,  A61K39/39

摘要： The present disclosure provides a subunit vaccine of contagious caprine pleuropneumonia and preparation method and use thereof, belonging to the technical field of preparation of animal infectious disease vaccine. The combination of Mycoplasma capricolum subsp. capripneumoniae immunoproteins comprises Mycoplasma capricolum subsp. capripneumoniae immunoproteins A, B, C, D and E; the mass ratio of Mycoplasma capricolum subsp. capripneumoniae immunoproteins A, B, C, D and E is (0.5-1.5): (0.5-1.5): (0.5-1.5): (0.5-1.5): (0.5-1.5). The subunit vaccine of contagious caprine pleuropneumonia comprises the combination of Mycoplasma capricolum subsp. capripneumoniae immunoproteins and adjuvant; the subunit vaccine has the advantages of high safety, good immunization effect, high stability and minor adverse effects.