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公开(公告)号:US20070148255A1
公开(公告)日:2007-06-28
申请号:US11701326
申请日:2007-01-31
申请人: Paul Tardi , Troy Harasym , Murray Webb , Clifford Shew , Marcel Bally , Lawrence Mayer , Andrew Janoff , Trevor Shew , Dominic Shew
发明人: Paul Tardi , Troy Harasym , Murray Webb , Clifford Shew , Marcel Bally , Lawrence Mayer , Andrew Janoff , Trevor Shew , Dominic Shew
IPC分类号: A61K33/24 , A61K31/7072 , A61K31/704 , A61K31/4745 , A61K31/337 , A61K31/282 , A61K9/16
CPC分类号: A61K9/127 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K31/00 , A61K31/282 , A61K31/337 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
摘要: Methods to prepare compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents. The compositions exhibit non-antagonistic effects when combinations of drugs are administered.
摘要翻译: 制备组合物的方法,所述组合物包含与两种或多种试剂的非拮抗组合稳定相关的递送载体。 当施用药物组合时,组合物表现出非拮抗作用。
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公开(公告)号:US09271931B2
公开(公告)日:2016-03-01
申请号:US10553373
申请日:2004-04-16
申请人: Paul Tardi , Troy Harasym , Murray Webb , Clifford Shew , Lawrence Mayer , Andrew Janoff , Marcel Bally
发明人: Paul Tardi , Troy Harasym , Murray Webb , Clifford Shew , Andrew Janoff , Marcel Bally
IPC分类号: A61K9/127 , A61K9/00 , A61K31/00 , A61K31/282 , A61K31/337 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K31/7076 , A61K33/24 , A61K45/06
CPC分类号: A61K9/127 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K31/00 , A61K31/282 , A61K31/337 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
摘要: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
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公开(公告)号:US07850990B2
公开(公告)日:2010-12-14
申请号:US10417631
申请日:2003-04-16
申请人: Paul Tardi , Troy Harasym , Murray Webb , Clifford Shew , Marcel Bally , Lawrence Mayer , Andrew Janoff
发明人: Paul Tardi , Troy Harasym , Murray Webb , Clifford Shew , Marcel Bally , Lawrence Mayer , Andrew Janoff
IPC分类号: A61K9/127
CPC分类号: A61K9/127 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K31/00 , A61K31/282 , A61K31/337 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
摘要: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
摘要翻译: 包含与两种或多种试剂(例如抗肿瘤剂)的非拮抗组合稳定相关的递送载体的组合物在施用药物组合时可用于实现非拮抗作用。
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公开(公告)号:US20060240090A1
公开(公告)日:2006-10-26
申请号:US10551579
申请日:2004-04-02
申请人: Lawrence Mayer , Marcel Bally , Murray Webb , Paul Tardi
发明人: Lawrence Mayer , Marcel Bally , Murray Webb , Paul Tardi
IPC分类号: A61K31/7072 , A61K31/4745 , A61K9/127
CPC分类号: A61K31/4745 , A61K9/127 , A61K31/7072 , A61K2300/00
摘要: Compositions which comprise liposomes having stably associated therewith a camptothecin and a fluoropyrimidine are useful in achieving enhanced therapeutic effects when combinations of these drugs are administered.
摘要翻译: 包含与喜树碱稳定相关的脂质体和氟嘧啶的组合物在施用这些药物的组合时可用于实现增强的治疗效果。
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公开(公告)号:US20060193904A1
公开(公告)日:2006-08-31
申请号:US11256445
申请日:2005-10-21
申请人: Paul Tardi , Sharon Johnstone , Murray Webb , Marcel Bally , Sheela Abraham
发明人: Paul Tardi , Sharon Johnstone , Murray Webb , Marcel Bally , Sheela Abraham
CPC分类号: A61K31/7072 , A61K9/127 , A61K9/1271 , A61K9/1272 , A61K31/00 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
摘要: This invention relates to encapsulation of drugs and other agents into liposomes.
摘要翻译: 本发明涉及药物和其它试剂在脂质体中的包封。
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公开(公告)号:US20080044464A1
公开(公告)日:2008-02-21
申请号:US11842130
申请日:2007-08-20
申请人: Paul TARDI , Sharon Johnstone , Murray Webb , Marcel Bally , Sheela Abraham
发明人: Paul TARDI , Sharon Johnstone , Murray Webb , Marcel Bally , Sheela Abraham
IPC分类号: A61K9/127
CPC分类号: A61K31/7072 , A61K9/127 , A61K9/1271 , A61K9/1272 , A61K31/00 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
摘要: This invention relates to encapsulation of drugs and other agents into liposomes.
摘要翻译: 本发明涉及药物和其它试剂在脂质体中的包封。
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公开(公告)号:US07744921B2
公开(公告)日:2010-06-29
申请号:US11842130
申请日:2007-08-20
申请人: Paul Tardi , Sharon Johnstone , Murray Webb , Marcel Bally , Sheela Abraham
发明人: Paul Tardi , Sharon Johnstone , Murray Webb , Marcel Bally , Sheela Abraham
IPC分类号: A61K9/127
CPC分类号: A61K31/7072 , A61K9/127 , A61K9/1271 , A61K9/1272 , A61K31/00 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
摘要: This invention relates to encapsulation of drugs and other agents into liposomes.
摘要翻译: 本发明涉及药物和其它试剂在脂质体中的包封。
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公开(公告)号:US07238367B2
公开(公告)日:2007-07-03
申请号:US10264818
申请日:2002-10-03
申请人: Paul Tardi , Sharon Johnstone , Murray Webb , Marcel Bally , Sheela Abraham
发明人: Paul Tardi , Sharon Johnstone , Murray Webb , Marcel Bally , Sheela Abraham
IPC分类号: A61K9/127
CPC分类号: A61K31/7072 , A61K9/127 , A61K9/1271 , A61K9/1272 , A61K31/00 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
摘要: This invention relates to encapsulation of drugs and other agents into liposomes.
摘要翻译: 本发明涉及药物和其它试剂在脂质体中的包封。
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公开(公告)号:US20080107722A1
公开(公告)日:2008-05-08
申请号:US11719088
申请日:2005-11-18
申请人: Paul Tardi , Murray Webb , Sharon Johnstone , Pierrot Harvie , Lawrence Mayer
发明人: Paul Tardi , Murray Webb , Sharon Johnstone , Pierrot Harvie , Lawrence Mayer
IPC分类号: A61K9/127
CPC分类号: A61K9/127 , A61K9/1278
摘要: This invention relates to encapsulation of drugs and other agents into preformed delivery vehicles.
摘要翻译: 本发明涉及将药物和其它药剂包封到预成型递送载体中。
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公开(公告)号:US20050118250A1
公开(公告)日:2005-06-02
申请号:US10495666
申请日:2002-11-13
申请人: Paul Tardi , Murray Webb , Lawrence Mayer , Ludger Ickenstein
发明人: Paul Tardi , Murray Webb , Lawrence Mayer , Ludger Ickenstein
IPC分类号: A61K9/127 , A61K9/19 , A61K31/704 , A61K31/7072 , A61K33/24
CPC分类号: A61K9/1271 , A61K9/127 , A61K9/1278
摘要: Liposomes that contain at least 10 mol % of a negatively charged lipid coupled to an non-zwitterionic moiety are stable in the blood. Liposomes containing at least 1 mol % of such lipids may be frozen safely.
摘要翻译: 含有至少10摩尔%的与非两性离子部分偶联的带负电荷的脂质的脂质体在血液中是稳定的。 含有至少1摩尔%的这种脂质的脂质体可以安全地冷冻。
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