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1.发明申请METHODS AND SYSTEMS OF CONVEYING FINE STRUCTURE INFORMATION TO A COCHLEAR IMPLANT PATIENT 有权将精细结构信息传送给海绵体植入物的方法和系统公开(公告)号：US20100070000A1
公开(公告)日：2010-03-18
申请号：US12559759
申请日：2009-09-15
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/323 , A61N1/36036 , A61N1/36185
摘要： An exemplary method of conveying fine structure information to a cochlear implant patient includes dividing an audio signal into a plurality of analysis channels, generating electrical stimulation in accordance with the information contained within each of the analysis channels, applying the electrical stimulation to at least one stimulation site within a patient via a plurality of stimulation channels, and at least partially isolating one of the stimulation channels from a rest of the stimulation channels, wherein fine structure information is conveyed to the patient via the isolated stimulation channel. Corresponding methods and systems are also disclosed.
摘要翻译： 将精细结构信息传送到耳蜗植入患者的示例性方法包括将音频信号划分成多个分析通道，根据包含在每个分析通道内的信息产生电刺激，将电刺激应用于至少一个刺激 通过多个刺激通道在患者体内的位置，并且至少部分地将刺激通道中的一个与其余刺激通道隔离，其中精细结构信息经由隔离的刺激通道传送给患者。 还公开了相应的方法和系统。
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2.发明申请Multi-electrode stimulation to elicit electrically-evoked compound action potential 审中-公开多电极刺激引发电诱发复合动作电位公开(公告)号：US20080221640A1
公开(公告)日：2008-09-11
申请号：US10698097
申请日：2003-10-31
IPC分类号： A61N1/00
CPC分类号： A61N1/37247 , A61N1/36036
摘要： A multichannel neurostimulation device spatially spreads the excitation pattern in the target neural tissue by either: (1) rapid sequential stimulation of a small group of electrodes, or (2) simultaneously stimulating a small group of electrodes. Such multi-electrode stimulation stimulates a greater number of neurons in a synchronous manner, thereby increasing the amplitude of the extra-cellular voltage fluctuation and facilitating its recording. The electrical stimuli are applied simultaneously (or sequentially at a rapid rate) on selected small groups of electrodes while monitoring the evoked compound action potential (ECAP) on a nearby electrode. The presence of an observable ECAP not only validates operation of the implant device at a time when the patient may be unconscious or otherwise unable to provide subjective feedback, but also provides a way for the magnitude of the observed ECAP to be recorded as a function of the amplitude of the applied stimulus. From this data, a safe, efficacious and comfortable threshold level can be obtained which may be used thereafter as the initial setting of the stimulation parameters of the neurostimulation device, or to guide the setting of the stimulation parameters of the neurostimulation device.
摘要翻译： 多通道神经刺激装置通过以下方式之一将目标神经组织中的激发图案空间扩展：（1）快速连续刺激小组电极，或（2）同时刺激小组电极。 这种多电极刺激以同步方式刺激更多数量的神经元，从而增加细胞外电压波动的幅度并促进其记录。 电刺激同时（或以快速顺序）施加在选定的小组电极上，同时监测附近电极上的诱发化合物动作电位（ECAP）。 可观察到的ECAP的存在不仅在患者无意识或不能提供主观反馈的时候验证植入装置的操作，而且还提供了将所观察到的ECAP的大小记录为作为 施加的刺激的幅度。 从该数据可以获得安全，有效和舒适的阈值水平，其可以随后用作神经刺激装置的刺激参数的初始设置，或者指导神经刺激装置的刺激参数的设置。
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3.发明申请公开(公告)号：US20100318158A1
公开(公告)日：2010-12-16
申请号：US12861925
申请日：2010-08-24
CPC分类号： A61N1/36036
摘要： Errors in pitch (frequency) allocation within a cochlear implant are corrected in order to provide a significant and profound improvement in the quality of sound perceived by the cochlear implant user. In one embodiment, the user is stimulated with a reference signal, e.g., the tone “A” (440 Hz) and then the user is stimulated with a probe signal, separated from the reference signal by an octave, e.g., high “A” (880 Hz). The user adjusts the location where the probe signal is applied, using current steering, until the pitch of the probe signal, as perceived by the user, matches the pitch of the reference signal, as perceived by the user. In this manner, the user maps frequencies to stimulation locations in order to tune his or her implant system to his or her unique cochlea.
摘要翻译： 修正耳蜗植入物内的间距（频率）分配的误差，以便对由人工耳蜗植入物使用者感知到的声音的质量提供显着和深刻的改善。 在一个实施例中，用参考信号（例如，音调“A”（440Hz））刺激用户，然后用探测信号刺激用户，该探测信号与参考信号分开八度，例如高“A” （880Hz）。 用户使用当前转向来调整应用探测信号的位置，直到由用户感知到的探测信号的音高与用户感知到的参考信号的音调相匹配。 以这种方式，用户将频率映射到刺激位置，以便将他或她的植入系统调整到他或她的独特的耳蜗。
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4.发明授权Methods and systems for automatically determining a neural response threshold current level 有权自动确定神经反应阈值电流水平的方法和系统公开(公告)号：US07343200B2
公开(公告)日：2008-03-11
申请号：US11141825
申请日：2005-06-01
IPC分类号： A61N1/05
CPC分类号： A61B5/04001 , A61B5/7217
摘要： Methods of automatically determining a neural response threshold current level include identifying one or more neural response signals at one or more corresponding stimulation current levels, identifying one or more non-response signals at one or more corresponding stimulation current levels, and analyzing a trend between the neural response signals and the non-response signals. Systems for automatically determining a neural response threshold current level include one or more devices configured to identify one or more neural response signals at one or more corresponding stimulation current levels, identify one or more non-response signals at one or more corresponding stimulation current levels; and analyze a trend between the neural response signals and the non-response signals.
摘要翻译： 自动确定神经反应阈值电流水平的方法包括以一个或多个相应的刺激电流水平识别一个或多个神经反应信号，识别一个或多个相应刺激电流水平下的一个或多个非响应信号，以及分析 神经反应信号和非响应信号。 用于自动确定神经反应阈值电流水平的系统包括被配置为在一个或多个相应的刺激电流水平上识别一个或多个神经反应信号的一个或多个装置，以一个或多个对应的刺激电流水平识别一个或多个非响应信号; 并分析神经反应信号与非应答信号之间的趋势。
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5.发明授权公开(公告)号：US07920925B2
公开(公告)日：2011-04-05
申请号：US12861925
申请日：2010-08-24
IPC分类号： A61N1/00
CPC分类号： A61N1/36036
摘要： Errors in pitch (frequency) allocation within a cochlear implant are corrected in order to provide a significant and profound improvement in the quality of sound perceived by the cochlear implant user. In one embodiment, the user is stimulated with a reference signal, e.g., the tone “A” (440 Hz) and then the user is stimulated with a probe signal, separated from the reference signal by an octave, e.g., high “A” (880 Hz). The user adjusts the location where the probe signal is applied, using current steering, until the pitch of the probe signal, as perceived by the user, matches the pitch of the reference signal, as perceived by the user. In this manner, the user maps frequencies to stimulation locations in order to tune his or her implant system to his or her unique cochlea.
摘要翻译： 修正耳蜗植入物内的间距（频率）分配的误差，以便对由人工耳蜗植入物使用者感知到的声音的质量提供显着和深刻的改善。 在一个实施例中，用参考信号（例如，音调“A”（440Hz））刺激用户，然后用探测信号刺激用户，该探测信号与参考信号分开八度，例如高“A” （880Hz）。 用户使用当前转向来调整应用探测信号的位置，直到由用户感知到的探测信号的音高与用户感知到的参考信号的音调相匹配。 以这种方式，用户将频率映射到刺激位置，以便将他或她的植入系统调整到他或她的独特的耳蜗。
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6.发明授权Method and system to convey the within-channel fine structure with a cochlear implant 有权用耳蜗植入物输送通道内精细结构的方法和系统公开(公告)号：US07317945B2
公开(公告)日：2008-01-08
申请号：US10712078
申请日：2003-11-13
IPC分类号： A61N1/00
CPC分类号： A61N1/36036
摘要： The present invention provides a cochlear stimulation system and method for capturing and translating fine time structure (“FTS”) in incoming sounds and delivering this information spatially to the cochlea. The system comprises a FTS estimator/analyzer and a current navigator. An embodiment of the method comprises analyzing the incoming sounds within a time frequency band, extracting the slowly varying frequency components and estimating the FTS to obtain a more precise dominant FTS component within a frequency band. After adding the fine structure to the carrier to identify a precise dominant FTS component in each analysis frequency band (or stimulation channel), a stimulation current may be “steered” or directed, using the concept of virtual electrodes, to the precise spatial location (place) on the cochlea that corresponds to the dominant FTS component. This process is simultaneously repeated for each stimulation channel and each FTS component.
摘要翻译： 本发明提供了一种用于在输入声音中捕获和翻译精细时间结构（“FTS”）并将该信息在空间上传送到耳蜗的人工耳蜗刺激系统和方法。 该系统包括FTS估计器/分析器和当前导航器。 该方法的一个实施例包括分析时间频带内的输入声音，提取慢速变化的频率分量并估计FTS以获得频带内的更精确的主要FTS分量。 在将精细结构添加到载体以识别每个分析频带（或刺激通道）中的精确主要FTS分量之后，可以使用虚拟电极的概念将刺激电流“引导”或定向到精确的空间位置 位置）对应于主要FTS组分的耳蜗。 对于每个刺激通道和每个FTS组分同时重复该过程。
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7.发明授权Methods and systems for automatically identifying whether a neural recording signal includes a neural response signal 有权用于自动识别神经记录信号是否包括神经反应信号的方法和系统公开(公告)号：US07818052B2
公开(公告)日：2010-10-19
申请号：US11142152
申请日：2005-06-01
IPC分类号： A61B5/04
CPC分类号： A61B5/04001 , A61B5/4041 , A61B5/7217 , A61N1/36036
摘要： Methods of automatically identifying whether a neural recording signal includes a neural response signal include fitting an artifact model to a neural recording signal to produce a fitted artifact model signal, determining a strength-of-response metric that describes a distance of the neural recording signal from the fitted artifact model signal, and identifying the neural recording signal as including a neural response signal if the strength-of-response metric is above a pre-determined threshold. Corresponding systems are also described.
摘要翻译： 自动识别神经记录信号是否包括神经反应信号的方法包括将伪像模型拟合到神经记录信号以产生拟合的伪像模型信号，确定描述神经记录信号距离的距离强度的度量度量 拟合假象模型信号，并且如果响应强度度量高于预定阈值，则将神经记录信号识别为包括神经响应信号。 还描述了相应的系统。
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公开(公告)号：US20090264962A1
公开(公告)日：2009-10-22
申请号：US12495593
申请日：2009-06-30
IPC分类号： H04R25/00
CPC分类号： H04R25/70 , A61N1/36036
摘要： Methods and systems for modifying the parameters of at least one hearing device for a patient with residual hearing provide needed orchestration of acoustic and electric stimulation of patients wearing such devices.
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公开(公告)号：US07561920B2
公开(公告)日：2009-07-14
申请号：US11097611
申请日：2005-03-31
IPC分类号： A61N1/18
CPC分类号： H04R25/70 , A61N1/36036
摘要： Methods and systems for modifying the parameters of at least one hearing device for a patient with residual hearing provide needed orchestration of acoustic and electric stimulation of patients wearing such devices.
摘要翻译： 用于修改具有残留听力的患者的至少一个听力装置的参数的方法和系统为佩戴这种装置的患者提供对声学和电刺激的所需编排。
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10.发明授权Enhanced methods for determining iso-loudness contours for fitting cochlear implant sound processors 失效用于确定用于拟合人工耳蜗声音处理器的等响度轮廓的增强方法公开(公告)号：US07043303B1
公开(公告)日：2006-05-09
申请号：US10647372
申请日：2003-08-25
申请人： Edward H. Overstreet
发明人： Edward H. Overstreet
IPC分类号： A61N1/36
CPC分类号： A61N1/36036
摘要： Methods are taught to simplify the cochlear implant fitting process for various cochlear prostheses and stimulation strategies, including high rate stimulation strategies. For instance, patient self-programming is made possible. In addition, auto-fitting is made possible (particularly useful for very young patients and other patients for whom it is challenging to obtain feedback) using iso-neural response contours which can be linearly transposed to arrive at iso-loudness contours. Furthermore, M iso-loudness contours (or iso-neural contours) can be linearly transposed to determine T iso-loudness contours. In addition, wider pulse widths can be used to generate an iso-loudness contour whose shape can be used (via linear transposition) to program high-rate, narrow pulse width stimulation.
摘要翻译： 教导了简化用于各种耳蜗假体和刺激策略的人工耳蜗植入装配过程的方法，包括高速率刺激策略。 例如，患者自我编程成为可能。 此外，使用可以线性转置以达到等响度轮廓的等神经反应轮廓，自动拟合成为可能（对于非常年轻的患者和其他具有挑战性的获得反馈的患者特别有用）。 此外，M等响度轮廓（或等神经轮廓）可以被线性转置以确定T等响度轮廓。 此外，可以使用更宽的脉冲宽度来产生等响度轮廓，其形状可以被使用（通过线性位移）来编程高速率，窄脉冲宽度的刺激。
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