公开(公告)号：US12098145B2

公开(公告)日：2024-09-24

申请号：US18543599

申请日：2023-12-18

Applicant: Libra Therapeutics, Inc.

Inventor： James Guy Breitenbucher ,  Maria Pia Catalani ,  Ali Munaim Yousif

IPC: C07D263/48 ,  A61K31/422 ,  C07D413/04 ,  C07D413/12 ,  C07D413/14 ,  C07D491/048 ,  C07D491/056 ,  C07D491/08 ,  C07D491/107 ,  C07D495/10 ,  C07D498/04

CPC classification number: C07D413/04 ,  C07D263/48 ,  C07D413/12 ,  C07D413/14 ,  C07D491/048 ,  C07D491/056 ,  C07D491/08 ,  C07D491/107 ,  C07D495/10 ,  C07D498/04

Abstract: Described herein are oxazole TRPML1 agonists and pharmaceutical compositions comprising said agonists. The subject compounds and compositions are useful for the treatment of TRPML1-mediated disorders or diseases.