公开(公告)号：US20170107476A1

公开(公告)日：2017-04-20

申请号：US15294152

申请日：2016-10-14

申请人： Lonza Limited

发明人： Rex POLLEY ,  Matthew SARCOPSKI ,  Robert HORTON ,  Thomas ELLIS ,  Paul PEASE ,  John CHAPIN

IPC分类号： C12M1/36 ,  G01N30/86 ,  C12Q3/00

摘要： The disclosure is directed to a system and method for control of at least one bioreactor, other cell cultivation-related equipment, and systems containing any combination of these in a plant. For example, a Plant-Wide Control System (PWCS) or a Process Control System (PCS) may be divided into three main components: hardware (including operating systems, such as a controller communicating with one or more servers of a network associated with the PWCS, (2) software (such as a control module) for performing control, and (3) one or more instrument control loops, which may be used by the software to maintain certain process values. Moreover, a Height Equivalent of a Theoretical Plate (HETP) value and an asymmetry factor may be determined based on real-time analysis on a chromatography column, using PWCS components.