公开(公告)号：US06495157B1

公开(公告)日：2002-12-17

申请号：US09619930

申请日：2000-07-20

申请人： Lorraine Elisabeth Pena ,  Phil Bryan Bowman ,  Robert Shih-Liang Chao ,  Carolyn V. Pesheck

发明人： Lorraine Elisabeth Pena ,  Phil Bryan Bowman ,  Robert Shih-Liang Chao ,  Carolyn V. Pesheck

IPC分类号： A61F606

CPC分类号： A61K9/02 ,  A61K31/7056

摘要： A highly storage-stable composition for vaginal administration of clindamycin is disclosed which is useful for the treatment of bacterial vaginosis. The composition is a vaginal suppository containing an antimicrobially effective amount of clindamycin dispersed in a Hard Fat NF suppository base. Hard Fat NF suppository bases provide a clindamycin product having long term storage stability while providing efficacy against bacterial vaginosis which is equivalent to clindamycin vaginal creams.

摘要翻译： 公开了用于阴道给药克林霉素的高度储存稳定的组合物，其可用于治疗细菌性阴道炎。 该组合物是含有分散在硬脂肪NF栓剂基质中的抗微生物有效量的克林霉素的阴道栓剂。 硬脂肪NF栓剂碱提供具有长期储存稳定性的克林霉素产品，同时提供相当于克林霉素阴道霜的细菌性阴道炎的功效。