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公开(公告)号:US07524871B2
公开(公告)日:2009-04-28
申请号:US10497328
申请日:2002-12-03
申请人: Lucija Peterlin Mar{hacek over (s)}i{hacek over (c)} , Danijel Kikelj , Andreja Jurca , Petra Marinko , Alenka Trampu{hacek over (s)} Bakija , Mojca Stegnar , Dejan Delovi{hacek over (c)} , Andrej Prezelj , Slavko Pe{hacek over (c)}ar
发明人: Lucija Peterlin Mar{hacek over (s)}i{hacek over (c)} , Danijel Kikelj , Andreja Jurca , Petra Marinko , Alenka Trampu{hacek over (s)} Bakija , Mojca Stegnar , Dejan Delovi{hacek over (c)} , Andrej Prezelj , Slavko Pe{hacek over (c)}ar
IPC分类号: A61K31/4439 , C07D401/12
CPC分类号: C07D401/12 , C07D417/04
摘要: Novel thrombin inhibitors of the formula I (I)and pharmaceutically acceptable salts thereof are described wherein the substituents in the description have the specific meanings. The compounds are useful as thrombin inhibitors.
摘要翻译: 描述了式I(I)的新型凝血酶抑制剂及其药学上可接受的盐,其中描述中的取代基具有具体含义。 该化合物可用作凝血酶抑制剂。
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公开(公告)号:US20050165034A1
公开(公告)日:2005-07-28
申请号:US10497328
申请日:2002-12-03
申请人: Lucija Marsic , Danijel Kikelj , Andreja Jurca , Petra Marinko , Alenka Trampus Bakija , Mojca Stegnar , Dejan Delovic , Andrej Prezelj , Slavko Pecar
发明人: Lucija Marsic , Danijel Kikelj , Andreja Jurca , Petra Marinko , Alenka Trampus Bakija , Mojca Stegnar , Dejan Delovic , Andrej Prezelj , Slavko Pecar
IPC分类号: A61K31/00 , A61P7/02 , C07D213/00 , C07D231/00 , C07D239/00 , C07D277/00 , C07D401/12 , C07D417/04 , A61K31/517 , A61K31/4439 , C07D417/02 , C07D43/02
CPC分类号: C07D401/12 , C07D417/04
摘要: Novel thrombin inhibitors of the formula I (I)and pharmaceutically acceptable salts thereof are described wherein the substituents in the description have the specific meanings. The compounds are useful as thrombin inhibitors.
摘要翻译: 描述了式I(I)的新型凝血酶抑制剂及其药学上可接受的盐,其中描述中的取代基具有具体含义。 该化合物可用作凝血酶抑制剂。
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