公开(公告)号：US07027134B1

公开(公告)日：2006-04-11

申请号：US10934601

申请日：2004-09-03

申请人： Luis H. Garcia-Rubio ,  Catalina E. Alupoaei ,  Willard Harris ,  Alfredo Peguero ,  Edward P. Cutolo ,  German Felix Leparc

发明人： Luis H. Garcia-Rubio ,  Catalina E. Alupoaei ,  Willard Harris ,  Alfredo Peguero ,  Edward P. Cutolo ,  German Felix Leparc

IPC分类号： G01N33/48

CPC分类号： G01N21/31 ,  G01N21/49 ,  G01N33/6803 ,  Y02A50/53 ,  Y02A50/58

摘要： The present invention provides a method and apparatus for the detection of an infectious disease or disorder in a fluid, such as a mammalian blood sample, the detection of a specific protein in a urine sample, or the detection of a particle in a plasma. The identification of the particles of interest is enable by taking a transmission spectrum of a test sample in at least a portion of the ultraviolet, visible, near-infrared portion of the spectrum and comparing the spectrum with a standard sample spectrum. From the comparison it is then determined whether the fluid from the test sample contains an particle of interest, and an identity of the particle of interest is determined. Spectroscopic and multiwavelength turbidimetry techniques provide a rapid, inexpensive, and convenient means for diagnosis. The comparison and determination steps may be performed visually or by spectral deconvolution.

摘要翻译： 本发明提供了用于检测流体（例如哺乳动物血液样品），尿样中特异性蛋白质的检测或血浆中的颗粒的检测中的感染性疾病或病症的方法和装置。 通过在光谱的紫外线，可见光，近红外部分的至少一部分中获取测试样品的透射光谱并将光谱与标准样品光谱进行比较，可以实现感兴趣的颗粒的识别。 从比较中，确定来自测试样品的流体是否含有感兴趣的颗粒，并确定感兴趣的颗粒的身份。 光谱和多波长比浊法技术为诊断提供了快速，便宜和方便的手段。 比较和确定步骤可以通过视觉或通过光谱去卷积来执行。