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公开(公告)号:US06511799B1
公开(公告)日:2003-01-28
申请号:US09311551
申请日:1999-05-14
IPC分类号: C12Q100
CPC分类号: C07K14/4702 , C07K14/705 , C12Q1/6897
摘要: Human CDX2, a homeobox gene, has been identified as a downstream effector of tumor suppressor APC. APC induces the transcription of CDX2. This newly found relationship permits specific drug screening assays as well as therapeutic and diagnostic methods.
摘要翻译: 人CDX2是同源盒基因,已被鉴定为肿瘤抑制因子APC的下游效应物。 APC诱导CDX2的转录。 这种新发现的关系允许特定的药物筛选测定以及治疗和诊断方法。