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公开(公告)号:US20200261486A1
公开(公告)日:2020-08-20
申请号:US16275531
申请日:2019-02-14
IPC分类号: A61K31/7048 , A61P35/00 , A61K35/30
摘要: Provided are compositions and methods for treatment of cancer and for adoptive T cell therapy (ACT). The compositions comprise one or more derivatives of tricin 7-O-β-D-glucopyranoside (ANTARTINA®). The compositions comprise one or more pharmaceutically acceptable excipients convenient for delivery of the tricin 7-O-β-D-glucopyranoside derivatives. Tricin 7-O-β-D-glucopyranoside derivatives described herein include acetylated tricin 7-O-β-D-glucopyranoside, as well as glucose, maltose, cellobiose, lactose, xylose, and galactose derivatives. The methods include treatment, or reduction in the risk of suffering from, colorectal cancer and hepatocellular cancer.