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公开(公告)号：US10722517B2
公开(公告)日：2020-07-28
申请号：US15572456
申请日：2016-05-09
IPC分类号： A61K31/428 , A61K31/4985 , A61K31/5377 , A61P35/00 , A61K45/06 , A61K31/4439 , A61P25/00 , A61K31/416 , A61K31/4184 , A61K31/423 , A61K31/426 , A61K31/437 , A61K31/4406 , A61K31/47 , A61K31/496 , A61K31/517 , A61K31/519
摘要： In certain embodiments the present invention provides methods useful in the treatment of glioma, such as glioblastoma, such methods comprising administering to a subject in need thereof a CSF-IR inhibitor together with one or more additional active agents such as IGF-IR inhibitors, PI3K inhibitors, IL4 inhibitors, NFAT inhibitors, and/or Stat6 inhibitors. In certain embodiments the present invention provides pharmaceutical compositions comprising a CSF-IR inhibitor together with one or more of such additional active agents.
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公开(公告)号：US20180125852A1
公开(公告)日：2018-05-10
申请号：US15572456
申请日：2016-05-09
IPC分类号： A61K31/5377 , A61K31/519 , A61K31/517 , A61K31/496 , A61K31/47 , A61K31/4406 , A61K31/437 , A61K31/428 , A61K31/426 , A61K31/423 , A61K31/4184 , A61K31/416 , A61K45/06 , A61P25/00 , A61P35/00
CPC分类号： A61K31/5377 , A61K31/416 , A61K31/4184 , A61K31/423 , A61K31/426 , A61K31/428 , A61K31/437 , A61K31/4406 , A61K31/4439 , A61K31/47 , A61K31/496 , A61K31/4985 , A61K31/517 , A61K31/519 , A61K45/06 , A61K2300/00 , A61P25/00 , A61P35/00
摘要： In certain embodiments the present invention provides methods useful in the treatment of glioma, such as glioblastoma, such methods comprising administering to a subject in need thereof a CSF-IR inhibitor together with one or more additional active agents such as IGF-IR inhibitors, PI3K inhibitors, IL4 inhibitors, NFAT inhibitors, and/or Stat6 inhibitors. In certain embodiments the present invention provides pharmaceutical compositions comprising a CSF-IR inhibitor together with one or more of such additional active agents.
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