-
公开(公告)号:US20200268793A1
公开(公告)日:2020-08-27
申请号:US15931027
申请日:2020-05-13
IPC分类号: A61K35/17 , C07K14/715 , C07K14/725 , C07K14/705 , A01K67/027
摘要: The present disclosure provides methods and compositions for treating cancers and pathogens. It relates to an immunoresponsive cell comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)), and expressing a secretable IL-1Ra polypeptide.