公开(公告)号：US20180009754A1

公开(公告)日：2018-01-11

申请号：US15544837

申请日：2016-01-20

Applicant: MERIAL, INC.

Inventor： Alan Long ,  Dpuglas Edward Wilkinson

IPC: C07D213/74 ,  A61K45/06 ,  A61K31/496

CPC classification number: C07D213/74 ,  A61K31/496 ,  A61K45/06 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D417/12 ,  C07D487/04

Abstract: The present invention relates to novel anthelmintic compounds of formula (IA) below: wherein, Y is selected from the group consisting of —H, aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocyclyl, alkyl, haloalkyl, and alkoxyalkyl; and Z is selected from the group consisting of aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocyclyl, alkyl, haloalkyl, and alkoxyalkyl. Variables Ring A, Ring B, Ring C, X1, X6, and X8 are as defined herein. The invention also relates to parasiticidal compositions comprising the compounds, and methods and uses of the compounds for treating and preventing parasitic infections and infestations in animals.