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1.
公开(公告)号:US20170296577A1
公开(公告)日:2017-10-19
申请号:US15487323
申请日:2017-04-13
申请人: MERIAL INC. , GENZYME CORPORATION
IPC分类号: A61K31/787 , A61K39/12 , A61K31/444 , A61K39/04 , C12N7/00 , A61K39/00
摘要: The present invention relates to non-mercurial preservatives, including antimicrobial polyamide polymers and octenidine, and to methods of use thereof to produce preservative-containing multi-dose formulations. The preservative-containing multi-dose formulations exhibit resistance to one or more contaminating microorganisms, and have advantageous properties with respect to long term stability of biological and small molecule active ingredients.
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公开(公告)号:US10583154B2
公开(公告)日:2020-03-10
申请号:US15487323
申请日:2017-04-13
IPC分类号: A61K31/787 , A61K47/18 , A61K47/34 , A61K31/444 , A61K39/04 , A61K39/12 , C12N7/00 , A61K39/00 , A61K39/02
摘要: The present invention relates to non-mercurial preservatives, including antimicrobial polyamide polymers and octenidine, and to methods of use thereof to produce preservative-containing multi-dose formulations. The preservative-containing multi-dose formulations exhibit resistance to one or more contaminating microorganisms, and have advantageous properties with respect to long term stability of biological and small molecule active ingredients.
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