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公开(公告)号:US20210254009A1
公开(公告)日:2021-08-19
申请号:US17187459
申请日:2021-02-26
Applicant: METCELA INC.
Inventor: Takahiro IWAMIYA , Tomoyuki OSUGI , Masaya SUZUKI
Abstract: It was found that culturing of fibroblasts in the presence of effective amounts of Tumor Necrosis Factor-alpha (TNF-α) known as a factor that induces hemorrhagic necrosis of tumor and Interleukin-4 (IL-4) known for its role in onset of allergic reactions leads to increase in the number of CD106-positive and G-CSF-positive fibroblasts.