公开(公告)号：US20210275499A1

公开(公告)日：2021-09-09

申请号：US17258273

申请日：2019-07-05

申请人： METRION BIOSCIENCES LIMITED

发明人： Marc ROGERS ,  Robert KIRBY ,  Gakujun SHOMI ,  Takuya MATSUO ,  Satoru KOBAYASHI ,  Junichiro KANAZAWA ,  Nobutaka YAMAOKA ,  Makoto TORIZUKA ,  Koichi SUZAWA

IPC分类号： A61K31/4164 ,  C07D233/28 ,  C07D405/12 ,  C07D403/06 ,  C07D401/06 ,  C07D401/12 ,  C07D471/08 ,  C07D403/12 ,  C07D235/02 ,  C07D491/107 ,  A61K31/4178 ,  C07D409/12 ,  A61K31/454 ,  A61K31/4439 ,  A61K31/46 ,  A61K31/439 ,  A61K31/55 ,  A61K31/5377

摘要： The invention relates to heterocyclic sulfonamide derivatives and their use in the treatment and prophylaxis of autoimmune, inflammatory, cardiovascular, neuronal, auditory, renal and metabolic mediated diseases, and to compositions containing said derivatives and processes for their preparation.