公开(公告)号：US20240075029A1

公开(公告)日：2024-03-07

申请号：US18255262

申请日：2021-12-01

申请人： METRIOPHARM AG

发明人： Wolfgang BRYSCH ,  Astrid KAISER ,  Petra SCHULZ ,  Sara SCHUMANN ,  Jörg WEGERER

IPC分类号： A61K31/502 ,  A61K45/06 ,  A61P31/14

CPC分类号： A61K31/502 ,  A61K45/06 ,  A61P31/14

摘要： The present application relates to the use of a phthalazinedione in the prevention or treatment of sequelae of a SARS-CoV-2 infection. Pharmaceutical compositions, combinations, advantageous formulation techniques and a method of treatment are disclosed.

公开(公告)号：US20230218614A1

公开(公告)日：2023-07-13

申请号：US18001034

申请日：2021-06-09

申请人： METRIOPHARM AG

发明人： Wolfgang BRYSCH ,  Astrid KAISER ,  Petra SCHULZ ,  Sara SCHUMANN ,  Jörg VON WEGERER ,  Christian SETZ ,  Ulrich SCHUBERT

IPC分类号： A61K31/502 ,  A61P31/14 ,  A61K45/06

CPC分类号： A61K31/502 ,  A61K45/06 ,  A61P31/14

摘要： The present application relates to the use of a phthalazinedione in the prevention or treatment of coronaviral infections. Pharmaceutical compositions, combinations and advantageous formulation techniques are disclosed.

公开(公告)号：US20230241060A1

公开(公告)日：2023-08-03

申请号：US18004806

申请日：2021-07-08

申请人： METRIOPHARM AG

发明人： Wolfgang BRYSCH ,  Jörg VON WEGERER ,  Beatte LUDESCHER ,  Sara SCHUMANN ,  Astrid KAISER ,  Petra SCHULZ

IPC分类号： A61K31/502 ,  A61K31/573 ,  A61P1/00 ,  A61P19/02 ,  A61P29/00

CPC分类号： A61K31/502 ,  A61K31/573 ,  A61P1/00 ,  A61P19/02 ,  A61P29/00

摘要： 5-amino-2,3-dihydro-1,4-phthalazinedione or one of its pharmaceutically acceptable salts for use as corticoid-sparing agent and pharmaceutical combinations comprising said glucocorticoid-sparing agent and a glucocorticoid for use in the prophylaxis and/or treatment of conditions or diseases usually treated with glucocorticoids are disclosed, as well as suitable application forms, pharmaceutical compositions and their prophylactic or therapeutic uses.