Method for producing 3,4-dihydroisoquinoline derivatives and production intermediates of same
    1.
    发明授权
    Method for producing 3,4-dihydroisoquinoline derivatives and production intermediates of same 有权
    制备3,4-二氢异喹啉衍生物的方法及其生产中间体

    公开(公告)号:US09193706B2

    公开(公告)日:2015-11-24

    申请号:US14347426

    申请日:2012-09-28

    摘要: Provided are an efficient method for producing 3,4-dihydroisoquinoline derivatives and useful production intermediates thereof. Provided is a method for producing 3,4-dihydroisoquinoline derivatives represented by general formula (1), comprising converting a compound represented by general formula (3) in the presence of acid after reacting with an aniline derivative, or converting a compound represented by general formula (3) by reacting with an aniline derivative in the presence of an acid.

    摘要翻译: 提供了一种生产3,4-二氢异喹啉衍生物的有效方法及其有用的生产中间体。 本发明提供通式(1)表示的3,4-二氢异喹啉衍生物的制造方法,其特征在于,在与苯胺衍生物反应后,在酸的存在下,使通式(3)表示的化合物转化,或者将通式 式(3)与苯胺衍生物在酸的存在下反应。

    METHOD FOR PRODUCING 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND PRODUCTION INTERMEDIATES OF SAME
    2.
    发明申请
    METHOD FOR PRODUCING 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND PRODUCTION INTERMEDIATES OF SAME 有权
    生产3,4-二氢喹啉衍生物的方法及其生产中间体

    公开(公告)号:US20140228576A1

    公开(公告)日:2014-08-14

    申请号:US14347426

    申请日:2012-09-28

    IPC分类号: C07D401/04 C07D217/16

    摘要: Provided are an efficient method for producing 3,4-dihydroisoquinoline derivatives and useful production intermediates thereof. Provided is a method for producing 3,4-dihydroisoquinoline derivatives represented by general formula (1), comprising converting a compound represented by general formula (3) in the presence of acid after reacting with an aniline derivative, or converting a compound represented by general formula (3) by reacting with an aniline derivative in the presence of an acid.

    摘要翻译: 提供了一种生产3,4-二氢异喹啉衍生物的有效方法及其有用的生产中间体。 本发明提供通式(1)表示的3,4-二氢异喹啉衍生物的制造方法,其特征在于,在与苯胺衍生物反应后,在酸的存在下,使通式(3)表示的化合物转化,或者将通式 式(3)与苯胺衍生物在酸的存在下反应。