公开(公告)号：US20230174955A1

公开(公告)日：2023-06-08

申请号：US17759881

申请日：2021-02-12

Applicant: Modern Meadow, Inc.

Inventor： Lixin DAI ,  Poonam SRIVASTAVA ,  Sumreet Singh JOHAR ,  Shashwat Mohan VAJPEYI ,  Mahadevan LAKSHMINARASIMHAN ,  James Egan WELCH

IPC: C12N9/02 ,  C07K14/78

CPC classification number: C12N9/0071 ,  C07K14/78 ,  C12Y114/11002

Abstract: The disclosure herein provides a monomeric prolyl 4-hydroxylase. A microorganism including a monomeric prolyl 4-hydroxylase is provided. The disclosure provides a microorganism including a monomeric prolyl 4-hydroxylase; and another protein to be hydroxylated. A method for providing skincare benefits including applying the fusion protein of the present disclosure on skin is also taught.

公开(公告)号：US20190092838A1

公开(公告)日：2019-03-28

申请号：US16125320

申请日：2018-09-07

Applicant: MODERN MEADOW, INC.

Inventor： Lixin DAI ,  Poonam SRIVASTAVA

IPC: C07K14/78 ,  C12N15/81 ,  C12R1/84 ,  C12N9/02 ,  C12N9/04 ,  C12N9/18 ,  C12N9/12 ,  C12N9/90

Abstract: This invention relates to genetically engineered strains of yeast and methods for producing recombinant protein (e.g., collagen). Recombinant protein of the present invention is used to produce biofabricated leather or a material having leather-like properties containing recombinant or engineered collagen. The yeast strains are engineered to produce ascorbate and/or increased production of α ketoglutarate.