公开(公告)号：US20180346588A1

公开(公告)日：2018-12-06

申请号：US15762885

申请日：2016-09-23

Applicant: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH ,  GREEN CROSS CORPORATION

Inventor： Dong-Sik KIM ,  Eun Jung SONG ,  Mijung LEE ,  Eun-Hee LEE ,  Miyoung OH ,  Jae Chan PARK ,  Kisu KIM ,  Sujeong KIM ,  Hyung-Kwon LIM ,  Kyuhyun LEE ,  Jongwha WON ,  Soongyu CHOI ,  Young Seoub PARK

IPC: C07K16/30

CPC classification number: C07K16/30 ,  C07K16/18 ,  C07K2317/21 ,  C07K2317/565 ,  C07K2317/92

Abstract: The present invention relates to an antibody specifically bound to mesothelin (MSLN), a nucleic acid encoding the antibody, a vector and a host cell including the nucleic acid, a method for producing the antibody, and a pharmaceutical composition for treating cancer or tumor including the antibody as an active ingredient. The antibody specifically bound to the mesothelin according to the present invention has high affinity and specificity to an antigen, such that it is possible to develop an antibody effectively usable for treatment or diagnosis of cancer or tumor diseases.