公开(公告)号：US20160058782A1

公开(公告)日：2016-03-03

申请号：US14830835

申请日：2015-08-20

Applicant: MORISHITA JINTAN CO., LTD.

Inventor： Norihisa NISHIDA ,  Akifumi NAGATOMO ,  Hideyuki ITO

IPC: A61K31/7048 ,  A61Q19/08 ,  A61K36/185 ,  A61K8/60

CPC classification number: A61K31/7048 ,  A23L2/52 ,  A23L2/66 ,  A23L3/3472 ,  A23L5/27 ,  A23L33/105 ,  A23L33/17 ,  A23V2002/00 ,  A61K8/347 ,  A61K8/498 ,  A61K8/60 ,  A61K31/366 ,  A61K36/185 ,  A61Q19/08 ,  A23V2200/302 ,  A23V2200/328 ,  A23V2250/2132 ,  A23V2250/5422 ,  A61K2300/00

Abstract: A Maillard reaction inhibitor which effectively inhibits the progress of a Maillard reaction in a living body, can be safely applied without adverse side effects, can be manufactured without any complicated process, a skin anti-aging agent, an anti-diabetic complication agent and foods and beverages using the same. The Maillard reaction inhibitor contains 50 to 90% by mass of polyphenol as an active ingredient. The Maillard reaction inhibitor has a potent Maillard reaction inhibitory activity in a living body and allows for the prevention and improvement of the various dysfunction of protein in a living body. Due to this activity, the Maillard reaction inhibitor suppresses aging and can prevent and/or treat diabetic complications. Furthermore, when the above-described tannin is mixed in foods and beverages containing collagen, it is possible to suppress the Maillard reaction in the foods and beverages to suppress the deterioration of the foods and beverages.

Abstract translation: 有效抑制美拉德反应在生物体中进行的美拉德反应抑制剂可以安全应用，无不良副作用，无需任何复杂的过程即可制造，皮肤抗老化剂，抗糖尿病并发症药物和食品 和使用其的饮料。 美拉德反应抑制剂含有50〜90质量％的多酚作为活性成分。 美拉德反应抑制剂在活体中具有强的美拉德反应抑制活性，并且能够预防和改善活体中蛋白质的各种功能障碍。 由于这种活性，美拉德反应抑制剂抑制衰老并且可以预防和/或治疗糖尿病并发症。 此外，当将上述单宁混合在含有胶原蛋白的食品和饮料中时，可以抑制食品和饮料中的美拉德反应，以抑制食品和饮料的劣化。