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公开(公告)号:US20240180219A1
公开(公告)日:2024-06-06
申请号:US18552544
申请日:2022-03-30
Applicant: MORISHITA JINTAN CO., LTD.
Inventor: Kentarou NAGAE , Takehiro NISHIKAWA , Osami NAKANO , Yunosuke NAKATA , Katsutoshi ISHII
Abstract: The present invention provides a seamless capsule that does not soften even in a high-temperature and high-humidity environment, maintains hardness in a tropical zone, etc., and can perceive the breakage of the capsule provided by applying a force to the capsule. The present invention relates to a seamless capsule including a capsule content and a shell layer that coats the capsule content, and a method for producing the same. The shell layer comprises at least deacylated gellan gum and modified starch. The capsule content comprises an oily component.
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公开(公告)号:US20230285923A1
公开(公告)日:2023-09-14
申请号:US18006650
申请日:2021-07-28
Applicant: MORISHITA JINTAN CO., LTD.
Inventor: Takehiro NISHIKAWA , Taku HASHIMOTO , Hideo SUGIMOTO , Ai NISHIBAYASHI
IPC: B01J13/16
CPC classification number: B01J13/16
Abstract: The present invention easily provides microcapsules by using a production method according to a more efficient and reliable interfacial polymerization method even when it is difficult to produce microcapsules by an interfacial polymerization method by adding a solution of a film-forming substance. Specifically, the present invention provides a method for producing microcapsules using two types of emulsion particles differing in size, the method comprising:
an emulsion-forming step of separately forming two types of emulsions (1) and (2) whose continuous phases are common, wherein emulsion particles (1) of the emulsion (1) comprises one of two types of monomers which react with each other to form a film and emulsion particles (2) of the emulsion (2) comprises the other monomer; and
a microcapsule-forming step of mixing and interfacial-polymerizing the emulsion (1) and the emulsion (2),
wherein
the emulsion particles (1) of the emulsion (1) have an average particle size (R) of 0.1 to 300 μm,
the emulsion particles (2) of the emulsion (2) have an average particle size (r) of 0.01 to 30 μm, and
r/R≤0.1 is satisfied.-
公开(公告)号:US20220226252A1
公开(公告)日:2022-07-21
申请号:US17595908
申请日:2020-06-12
Applicant: MORISHITA JINTAN CO., LTD.
Inventor: Takehiro NISHIKAWA , Katsutoshi ISHII , Kazuma TAKAHASHI
IPC: A61K9/48 , A61K31/375 , A61K35/744 , A61K31/19
Abstract: An object of the present invention is to provide a technique for delaying disintegration of a capsule by blending a certain component in a core of the capsule, and to increase the degree of freedom in capsule design. The present invention relates to a delayed disintegration-type seamless capsule that is a seamless capsule including a core, one or more intermediate layers formed on the core, and an outermost layer formed on the intermediate layers, wherein the core contains an active substance, an amphoteric surfactant, and a fat having a melting point of 40° C. or more, at least one layer of the intermediate layers contains a fat having a melting point of 45° C. or more, and the outermost layer contains a water-soluble natural polymer. The present invention also relates to a method for producing the same.
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