公开(公告)号：US20190070170A1

公开(公告)日：2019-03-07

申请号：US15695304

申请日：2017-09-05

Applicant: Macau University of Science and Technology

Inventor： Hua Zhou ,  Jian-Xin Liu ,  Jin-Fang Luo ,  Chun-Song Chen ,  Elaine Lai-Han Leung ,  Liang Liu

IPC: A61K31/485 ,  G01N33/573 ,  C12Q1/68

Abstract: A method of selectively inhibiting the overexpression of mPGES-1 in a subject in need thereof includes a step of administering an effective amount of a selective mPGES-1 inhibitor or a salt thereof to the subject. A method of treating a subject suffering from a disease associated with an overexpression of mPGES-1 and having a risk of cardiovascular event includes the step of administering an effective amount of a selective mPGES-1 inhibitor to the subject.