公开(公告)号：US09522125B1

公开(公告)日：2016-12-20

申请号：US14945436

申请日：2015-11-19

Applicant: Macau University of Science and Technology

Inventor： Xiao-Jun Yao ,  Lai-Han Leung ,  Lian-Xiang Luo ,  Wen-Luan Hsiao ,  Liang Liu

IPC: A61K31/136

CPC classification number: A61K31/136

Abstract: The present invention discloses that a method of treating cancer, preferably non-small cell lung cancer, comprises administrating mitoxantrone. The present invention also discloses a method of inhibiting ROS1 kinase comprising administrating mitoxantrone. A pharmaceutical composition comprising mitoxantrone is also disclosed.

Abstract translation: 本发明公开了一种治疗癌症，优选非小细胞肺癌的方法，包括给予米托蒽醌。 本发明还公开了抑制ROS1激酶的方法，其包括施用米托蒽醌。 还公开了包含米托蒽醌的药物组合物。