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公开(公告)号:US07619067B2
公开(公告)日:2009-11-17
申请号:US11383798
申请日:2006-05-17
申请人: Madan M. Paidhungat , Ian J. Sas , Thomas Bouquin , David Lin , Teddy Chen , Douglas Guptill , Amy Brideau-Andersen , Steven H. Bass , Phillip A. Patten
发明人: Madan M. Paidhungat , Ian J. Sas , Thomas Bouquin , David Lin , Teddy Chen , Douglas Guptill , Amy Brideau-Andersen , Steven H. Bass , Phillip A. Patten
摘要: The present invention provides evolved interferon-alpha polypeptides, and conjugates thereof, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.
摘要翻译: 本发明提供了进化型干扰素-α多肽及其缀合物,以及编码多肽的核酸。 本发明还包括包含这些多肽,缀合物和核酸的组合物; 含有或表达多肽,缀合物和核酸的细胞; 制备多肽,缀合物和核酸的方法; 以及使用多肽,缀合物和核酸的方法。